Abstract
The electrophilic trichloromethylation of 3-chloro-, 3-bromo-, and 3,4-dibromothiophene was studied. It is shown that reaction is directed towards position 2, accompanied by frequent formation of the corresponding substituted di-(2-thienyl)dichloromethane. Trichloromethylation of β-bromothiophenes is complicated by exchange of chlorine for bromine under the reaction conditions.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 8, pp. 1046–1048, August, 1993.
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Gromova, G.P., Belen'kii, L.I. & Krayushkin, M.M. Electrophilic trichloromethylation of some halogenated thiophenes. Chem Heterocycl Compd 29, 889–891 (1993). https://doi.org/10.1007/BF00534264
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DOI: https://doi.org/10.1007/BF00534264