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The ultrastructure of thyroid in chronic autoimmune thyroiditis

Die Ultrastruktur der chronischen Autoimmun-Thyreoiditis

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Zusammenfassung

6 Fälle von Autoimmunthyreoiditis (2 Fälle von chronischer asymptomatischer Thyreoiditis, 2 Fälle von Knotenstruma mit herdförmiger Thyreoiditis und 2 Fälle von Hashimoto-Thyreoiditis) werden licht- und elektronenoptisch untersucht. Die ultrastrukturellen Veränderungen stimmen in allen Fällen überein. Die cytologischen Veränderungen in den Follikelzellen machen eine erhöhte Stoffwechselaktivität wahrscheinlich. Als Besonderheit wird das aktive Eindringen von Lymphocyten und Plasmazellen in die Follikelepithelien (Emperipolese) hervorgehoben.

Summary

In an investigation of autoimmune thyroiditis, two cases of chronic asymptomatic thyroiditis, two cases of nodular goitre with focal thyroiditis and two cases of Hashimoto goitre were studied with the electron microscope. The ultrastructural observations were similar in the six cases. Cytological alterations of the follicle cells were found, some of which suggested an increased metabolic activity. Lymphocytes and plasmocytes established close relationships with the thyroid cells: emperipolesis was encountered.

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  1. Departments of Experimental Medicine Electron Microscopy and Pathology Faculty of Medicine, University of Brussels, Belgium

    P. Nève

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Nève, P. The ultrastructure of thyroid in chronic autoimmune thyroiditis. Virchows Arch. Abt. A Path. Anat. 346, 302–317 (1969). https://doi.org/10.1007/BF00542708

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  • DOI: https://doi.org/10.1007/BF00542708

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