Summary
Rabbits were anaesthetized with urethane and pentobarbitone sodium. The K+ and Na+ activity in the blood of the femoral vein or in the interstitial space of a skeletal muscle (vastus medialis of M. quadriceps femoris) were measured continuously by means of glass microelectrodes during stimulation of the muscles of the hindlimb. The blood flow in the femoral artery was recorded simultaneously by means of a Statham flowmeter. The K+ activity (at rest about 4 mmole/l) rose during the stimulation of the musculature. The course of the K+ increase was similar to that of the functional hyperemia. Maximum values obtained by frequent supramaximal stimulation (40 cps) were 6–6.5 mmole/l in the venous blood and 8–8.5 mmole/l in the interstitial space. The Na+ activity also rose from about 135 mmole/l to 136–140 mmole/l. The findings support the assumption that potassium shifts play a role in the regulation of functional hyperemia.
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Auszugsweise vorgetragen auf der Herbsttagung der Deutschen Physiologischen Gesellschaft in Erlangen, 1970.
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Gebert, G. Messung der K+- und Na+-Aktivität mit Mikro-Glaselektroden im Extracellulärraum des Kaninchenskeletmuskels bei Muskelarbeit. Pflugers Arch. 331, 204–214 (1972). https://doi.org/10.1007/BF00589127
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DOI: https://doi.org/10.1007/BF00589127