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Revascularization of free full thickness skin autografts

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Summary

The vascular system in experimental, free, full thickness skin autografts in guinea pigs was visualized by injecting Indian ink in the period between the 6th postoperative day and and eight weeks after the operation. Ideally, revascularization occurs by reactivation ofexisting vessels in the graft. Even reactivation of perifollicular vascular networks and the subepidermal vascular plexus is possible. If revascularization occurs through the growth ofnew vessels, for a long time the vascular arrangement is not the same as that in normal guinea pig skin. The epidermis usually shows acanthosis-like changes. Fast and effective revascularization minimizes the extent and duration of this change.

Zusammenfassung

Beim Meerschweinchen wurde das Gefäßsystem innerhalb experimentell gesetzter autologer freier Vollhauttransplantate durch Tuscheinjektion in einem Zeitraum zwischen dem 6. postoperativen Tag und 8 Wochen nach der Operation dargestellt. Die Revascularisation erfolgt im Idealfall durch Reaktivierung deralten Transplantatgefäße. Selbst eine Reaktivierung der perifollikulären Gefäßnetze und des subepidermalen Gefäßplexus ist möglich. Wenn es zu einer Revaskularisation durch Einwachsenneuer Gefäße kommt, so weicht die Gefäßanordnung über längere Zeiträume erheblich von der normaler Meerschweinchenhaut ab. Die Epidermis ist meist acanthoseähnlich verdickt. Dauer und Ausmaß dieser Veränderung sind um so geringer, je besser und schneller die Revascularisation erfolgt.

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Authors and Affiliations

  1. Department of Dermatology, Philipps-University Marburg, Lahn, Germany

    M. Gloor

  2. Department of Anatomy, Philipps-University Marburg, Lahn, Germany

    G. Ludwig

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  1. M. Gloor
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  2. G. Ludwig
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Gloor, M., Ludwig, G. Revascularization of free full thickness skin autografts. Arch. Derm. Forsch. 246, 211–221 (1973). https://doi.org/10.1007/BF00595421

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