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Aorto-coronary by-pass with autogenous saphenous vein grafts: Histopathological aspects

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Summary

The histological modifications in 8 cases of autologous aorto-coronary saphenous vein grafts were studied. In the early stages, these showed intimal thickening and medial hypertrophy, particularly affecting the middle circular layer. The intimal thickening progressed, and the media later became largely replaced by dense fibrous tissue. No aneurysmal dilatations were observed, but in 3 cases the grafts were thrombosed. The pathogenesis of these changes is discussed.

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Authors and Affiliations

  1. Department of Pathology, University of Geneva, Switzerland

    M. -C. Marti, B. Bouchardy & J. N. Cox

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  1. M. -C. Marti
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  2. B. Bouchardy
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  3. J. N. Cox
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Marti, M.C., Bouchardy, B. & Cox, J.N. Aorto-coronary by-pass with autogenous saphenous vein grafts: Histopathological aspects. Virchows Arch. Abt. A Path. Anat. 352, 255–266 (1971). https://doi.org/10.1007/BF00600675

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