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Swelling of poly(N-isopropylacrylamide) gels in water-aprotic solvent mixtures

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Abstract

The swelling volume of poly(N-isopropylacrylamide) (PIPAAm) gel in aprotic solvents (acetonitrile (AcN)-, tetrahydrofuran (THF)-, 1,4-dioxane (DO)- and dimethylsulfoxide (DMSO))-water mixtures was measured at 25°C. The gel swollen in water shrank first and then reswelled with addition of the aprotic solvents. At an intermediate mole fraction (XDMSO) range of DMSO-water mixtures, the gel demonstrated a “reentrant” swelling phenomenon the hydrated gel shrank first on addition of a small amount of solvent, showed a typical wide reentrant transition, and gradually reswelled in the range near pure solvent. On the other hand, the gels in AcN-, THF-, and DO-water mixtures demonstrated a “reentrant-convex” swelling phenomenon: the gels reswelled after a reentrant phase transition in low Xorg (XAcN, XTHF and XDO), showed a maximum swelling in the intermediate Xorg region, and shrank again gradually in the high Xorg region. Such a swelling behavior of the gel was interpreted by correlating with solution properties of the aqueous aprotic solvent mixtures.

The strength of hydrogen bonding around amide groups of the homopolymer was examined in pure solvents (water, THF, and DMSO) and in all proportion of aqueous THF to observe the relation with swelling behavior of gel by spectrum analysis of the amide I and II bands of Fourier Transform Infrared Spectroscopy (FT-IR). The swelling properties of gels in solvents and the aqueous mixtures were well correlated with the peak shifts of amide groups of the homopolymer.

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References

  1. Otake K, Inomata H, Konno M, Saito S (1990) macromolecules 23:283

    Google Scholar 

  2. Shield HG, Tirrel DA (1990) J Phys Chem 94:4352

    Google Scholar 

  3. Fujishige S, Kubota K, Ando I (1989) J Phys Chem 93:3313

    Google Scholar 

  4. Winnik FM (1990) Polymer 31:2125

    Google Scholar 

  5. Yamamoto I, Iwasaki K, Hirotsu S (1989) J Phys Soc Jpn 58:210

    Google Scholar 

  6. Matsuo ES, Hirokawa Y, Tanaka T (1988) J Chem Phys 89:1695

    Google Scholar 

  7. Hirokawa Y, Tanaka T (1981) J Chem Phys 81:6397

    Google Scholar 

  8. Winnik FM, Ringsdorf H, Venzmer J (1990) Macromolecules 23:2415

    Google Scholar 

  9. Hirotsu S (1988) J Chem Phys 88:427

    Google Scholar 

  10. Shield HG, Muthukumar M, Tirrell DA (1991) Macromolecules 24:948

    Google Scholar 

  11. Amiya T, Hirokawa Y, Hirose Y, Li Y, Tanaka T (1987) J Chem Phys 86:2375

    Google Scholar 

  12. Hirotsu S (1987) J Phys Soc Jpn 56:233

    Google Scholar 

  13. Katayama S, Hirokawa Y, Tanaka T (1984) Macromolecules 17:2641

    Google Scholar 

  14. Mukae K, Sakurai M, Sawamura S, Makino K, Kim SW, Ueda I, Shirahama K (1993) J Phys Chem 97:737

    Google Scholar 

  15. Majigosky WM, Warfield RW (1983) J Chem Phys 78:1912

    Google Scholar 

  16. Treiner C, Tzaias P, Chemila M (1976) J Chem Soc Faraday Trans 72:2007

    Google Scholar 

  17. Signer R, Arm H, Daeniker H (1969) Helv Chim Acta 52:233

    Google Scholar 

  18. Goates JR, Sullivan RJ (1958) J Phys Chem 62:188

    Google Scholar 

  19. Braue EH Jr, Panella MG (1987) Appl Spectrosc 41:1057

    Google Scholar 

  20. Gulke EA (1989) In: Brandip J, Inmergut EA (eds) Polymer Hand book, third Ed, John Wiley & Suns, New York, p519

    Google Scholar 

  21. Fedors RF (1974) Polym Eng Sci 2:152

    Google Scholar 

  22. Yagi Y, Inomata H, Saito S (1992) Macromolecules 25:2997

    Google Scholar 

  23. Rodante F, Marrosu G (1988) Thermochim Acta 136:209

    Google Scholar 

  24. Morcom KW, Smith RW (1970) Trans Faraday Soc 66:1073

    Google Scholar 

  25. Canabi S, Conti G, Lepori L (1979) J Phys Chem 83:463

    Google Scholar 

  26. Iwasaki K, Fujiyama T (1979) J Phys Chem 83:463

    Google Scholar 

  27. Arakawa K, Takenaka N, Sasaki K (1970) Bull Chem Soc Jpn 43:636

    Google Scholar 

  28. Atkinson G, Rajagopalon X, Atkinson BL (1981) J Phys Chem 85:733

    Google Scholar 

  29. Murthy NM, Naigabhushanam G (1984) Acousti lett 8:100

    Google Scholar 

  30. Wakisaka A, Shimizu N, Nishi K, Tokumaru K, Sakuragi H (1992) J Chem Soc Faraday Trans 88:1129

    Google Scholar 

  31. Davis MI (1983) Thermochim Acta 63:67

    Google Scholar 

  32. Kato T (1990) In: Matteori E and Mansoor GA (eds) Fluctuation Theory of Mixtures. Taylor & Francis, New York, 227

    Google Scholar 

  33. Ben-Naim A (1977) J Chem Phys 67:4884

    Google Scholar 

  34. Matteoli E, Lepori L (1984) J Chem Phys 80:2856

    Google Scholar 

  35. Subbarangaiaii K, Murthy NM, Subrahmangam SV (1981) Bull Chem Soc Jpn 54:2200

    Google Scholar 

  36. Hassun SK, Isa SD (1987) Acousti lett 10:110

    Google Scholar 

  37. Benson G, Darcy PJ, Handa YP (1981) Thermochim Acta 46, 296

    Google Scholar 

  38. Visser CD, Heuvelsland WJM, Dunn LD, Somsen G (1978) J Chem Soc Faraday Trans 74:1159

    Google Scholar 

  39. Kiyohara O, Perron G, Desnoyers JE (1975) Can J Chem 53:3263

    Google Scholar 

  40. Sakurai M (1992) J Chem Eng Data 37:492

    Google Scholar 

  41. Benson GC, Kiyohara O (1980) J Solution Chem 10:391

    Google Scholar 

  42. Kobayashi M, Nishioka K (1987) J Phys Chem 91:1247

    Google Scholar 

  43. Thompson WK, Hall DG (1967) Trans Faraday Soc 63:1553

    Google Scholar 

  44. Tsai Y, Ma S, Kamaya H, Ueda I (1989) Mol Pharmacol 31:623

    Google Scholar 

  45. Hazi D, Bratos I (1976) In: Schuster P, Zundel G, Sardorfy C (eds) The Hydrogen Bond. North-Holland Vol 2 p594

  46. Bellamy LJ (1975) In: Bellamy LJ (ed) The Infra-red Spectra of Complex Molecules. Hasted Press, a Division of John Wiley & Sons, New York, p245

    Google Scholar 

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Authors and Affiliations

  1. Tsukuba Research Laboratories, Hisamitsu Pharmaceutical Company, Inc., 1-25-11 Kannondai, 305, Tsukuba, Ibaraki, Japan

    K. Mukae

  2. Department of Polymer Science, Faculty of Science, Hokkaido University, Japan

    M. Sakurai

  3. Department of Chemistry, Faculty of Science and Engineering, Ritsumeikan University, Japan

    S. Sawamura

  4. Faculty of Pharmaceutical Sciences, Science University of Tokyo, Japan

    K. Makino

  5. Center for Controlled Chemical Delivery, Department of Pharmaceutics, University of Utah, Salt Lake City, USA

    S. W. Kim

  6. Anesthesia Service, Veterans Administration Medical, Center and Department of Anesthesia, School of Medicine, University of Utah, Salt Lake City, USA

    I. Ueda

  7. Department of Chemistry, Faculty of Science and Engineering, Saga University, Japan

    K. Shirahama

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  1. K. Mukae
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  2. M. Sakurai
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  3. S. Sawamura
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  4. K. Makino
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  5. S. W. Kim
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Mukae, K., Sakurai, M., Sawamura, S. et al. Swelling of poly(N-isopropylacrylamide) gels in water-aprotic solvent mixtures. Colloid Polym Sci 272, 655–663 (1994). https://doi.org/10.1007/BF00659279

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  • DOI: https://doi.org/10.1007/BF00659279

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