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Analysis of continuous fermentation processes in aqueous two-phase systems

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Abstract

Simulations of continuous ethanol or acetonobutylic fermentations in aqueous two-phase systems show that at high substrate feed concentrations it is possible to obtain solvent productivities about 25–40% higher than in conventional systems with cell recycle if the biomass bleed rate is kept about one tenth of the value of D.

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Abbreviations

a :

Volumetric fraction of dextran rich phase

B h−1 :

Bleed rate

D h−1 :

Dilution rate

P kg m−3 :

Product concentration

PD kg m−3 h−1 :

Productivity

S kg m−3 :

Substrate

X kg m−3 :

Biomass

β :

Partition coefficient

References

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Authors and Affiliations

  1. Institute of Chemical Engineering, Polish Academy of Sciences, Baltycka 5, 44-100, Gliwice, Poland

    A. B. Jarzębski & J. J. Malinowski

  2. Départment de Génie Biochimique et Alimentaire, UA-CNRS-N∘ 544 INSA, Av. Rangueil, 31077, Toulouse, France

    G. Goma & P. Soucaille

Authors
  1. A. B. Jarzębski
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  2. J. J. Malinowski
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  3. G. Goma
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  4. P. Soucaille
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Jarzębski, A.B., Malinowski, J.J., Goma, G. et al. Analysis of continuous fermentation processes in aqueous two-phase systems. Bioprocess Engineering 7, 315–317 (1992). https://doi.org/10.1007/BF00705161

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  • DOI: https://doi.org/10.1007/BF00705161

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