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The synthesis of some sterol and triterpenic glycosides

  • Chemistry
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Pharmaceutical Chemistry Journal Aims and scope

Conclusions

The synthesis of lanosterol,β-sitosterol, cholesterol, and panaxadiolβ-glycosides was accomplished. The feasibility of glycosylating diatomic triterpenic alcohols was demonstrated with panaxadiol. The glycosylation ofβ-sitosterol and cholesterol is accompanied by the formation of di-β-sitosterol and dicholesterol ethers. Synthetic panaxadiol monoside possesses a higher physiological activity than the original panaxadiol.

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Authors and Affiliations

  1. Institute of Biologically Active Substances, Dal'nevostochnii Section, Siberian Branch of the Academy of Sciences of the USSR, Vladivostok

    G. B. Elyakov, N. I. Uvarova, I. V. Dardymov, O. E. Mislitskaya & L. M. Antonik

Authors
  1. G. B. Elyakov
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  2. N. I. Uvarova
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  3. I. V. Dardymov
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  4. O. E. Mislitskaya
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  5. L. M. Antonik
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Additional information

Pharmacological portion.

Translated from Khimiko-Farmatsevticheskii Zhurnal, No. 6, pp. 5–8, June, 1969.

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Elyakov, G.B., Uvarova, N.I., Dardymov, I.V. et al. The synthesis of some sterol and triterpenic glycosides. Pharm Chem J 3, 308–310 (1969). https://doi.org/10.1007/BF00764129

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  • DOI: https://doi.org/10.1007/BF00764129

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