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Effect of long term feeding of rice bran oil upon lipids and lipoproteins in rats

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Abstract

The effects of feeding two levels of rice bran oil (RBO) on the growth, lipid parameters, and fatty acid composition of the plasma and liver of rats (Wistar strain) were compared with those produced on animals which had been fed the same levels of peanut oil (PNO). The control animals were fed synthetic diets containing 5 and 20% peanut oil (PNO) and the experimental groups were fed similar diets, containing the same level of rice bran oil (RBO). There was no significant difference with respect to the organ weights between the control and the experimental groups. In general, groups fed 20% oil gained more weight than groups fed 5% oil. The animals which received rice bran oil in their diet had, in general, comparatively lower levels of cholesterol, triglycerides and phospholipids. On the other hand, animals receiving 20% rice bran oil in their diet, showed an increase of 20% in high density lipoproteins (HDL-C), within 18 weeks (p<0.05), when compared to the animals fed with peanut oil. Similarly, low density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C) were lower in RBO-fed groups, than in the PNO-fed groups. There was, however, no significant differences in the cholesterol/phospholipid (C/P) ratio of the two groups. Analysis of plasma and of liver fatty acids indicated, in a general way, the type of fat consumed. There were no significant difference in the P/S ratio, nor any in the oleic/linoleic, oleic/stearic, palmitoleic/palmitic, oleic/palmitic, and oleic/palmitoleic ratios. Furthermore, levels of saturated (SAFA), monounsaturated (MUFA), and polyunsaturated (PUFA) fatty acids were identical in both the groups. Thus, our results suggest that feeding a high level of rice bran oil (RBO) has no deleterious effect on the growth and blood lipid profile of rats.

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Abbreviations

PNO:

peanut oil

RBO:

rice bran oil

HDL-C:

high density lipoprotein cholesterol

LDL-C:

low density lipoprotein cholesterol

VLDL-C:

very low density lipoprotein cholesterol

SAFA:

saturated fatty acids

MUFA:

mono-unsaturated fatty acids

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Authors and Affiliations

  1. Department of Biochemistry and Nutrition, Central Food Technological Research Institute, 570013, Mysore, India

    S. Purushothama, P. L. Raina & K. Hariharan

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  1. S. Purushothama
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  2. P. L. Raina
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Purushothama, S., Raina, P.L. & Hariharan, K. Effect of long term feeding of rice bran oil upon lipids and lipoproteins in rats. Mol Cell Biochem 146, 63–69 (1995). https://doi.org/10.1007/BF00926883

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  • DOI: https://doi.org/10.1007/BF00926883

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