Abstract
In an experiment including 8 groups of 15 mice, the effect of migratingAscaris suum larvae in the lungs on the establishment and pathogenicity of aerosol exposure toPasteurella multocida was investigated. Following aerosol exposure toP. multocida, mice with migratingA. suum in their lungs developed more severe pneumonia and septicaemia than did parasite-free mice. The parasite-induced effect on bacterial pathogenicity was more marked for a non-toxin-producingP. multocida as compared with a toxin-producing strain ofP. multocida, possibly due to the higher spontaneous pathogenicity of the non-toxigenic strain ofP. multocida. The present results should encourage controlled experiments on possible interactions betweenA. suum and various airborne microbial infections in pigs.
This is a preview of subscription content, log in via an institution to check access.
Similar content being viewed by others
References
Andersen S (1976) The influence ofAscaris suum upon growth rates in pigs. Nord Vet Med 28:322–330
Bækbo P (1989) Luftkvalitet og sundhed i svinestalde. Under søgelser af luftkvaliteten i danske svinestalde og patogenitetsstudier ved lungeinfektion medPasteurella multocida Ph.D. Thesis. Royal Veterinary and Agricultural University, Copenhagen
Cowan ST (1974) Cowan and Steel's manual for the identification of medical bacteria, 2nd edn. Cambridge University Press, Cambridge
Curtis SE, Tisch DA, Todd KS, Simon J (1986) Pulmonary bacterial deposition and clearance during ascarid larval migration in weanling pigs. Can J Vet Res 51:525–527
Eriksen L (1981) Host parasite relations inAscaris suum infection in pigs and mice. Thesis, Royal Veterinary and Agricultural University, Copenhagen
Eriksen L, Nansen P, Roepstorff A, Lind P, Nilsson O (1992) Response to repeated inoculations withAscaris suum eggs in pigs during the fattening period: I. Studies on worm kinetics. Parasitol Res (in press)
Foged NT, Nielsen JP, Pedersen KB (1988) Differentiation of toxigenic from nontoxigenic isolates ofPasteurella multocida by enzyme-linked immunosorbent assay. J Clin Microsc 26:1419–1420
Forsum EM, Nesheim C, Crompton DWT (1981) Nutritional aspects ofAscaris infection in young protein deficient pigs. Parasitology 83:497–512
Gois M, Kusa F, Sisak F (1980) Microbiological findings in the lungs of slaughter pigs. Proceedings, 6th Congress of the International Pig Veterinary Society, Copenhagen June 30–July 3
Hale OM, Stewart TB, Marti OG (1985) Influence of an experimental infection ofAscaris suum on performance of pigs. J Anim Sci 60:220–225
Lloyd S, Soulsby EJL (1985) Ascariasis in animals. In: Crompton DWT, Nesheim MC, Pawlowski ZS (eds) Ascariasis and its public health significance 1st edn. Taylor & Francis, London Philadelphia, pp 25–36
Oksanen A, Eriksen L, Roepstorff A, Ilsøe B, Nansen P, Lind P (1990) Embryonation and infectivity ofAscaris suum. A comparison of eggs collected from worm uteri with eggs isolated from pig faeces. Acta Vet Scand 31:393–398
Roneus O (1966) Studies on the aethiology and pathogenesis of white spots in the liver of pigs (thesis). Acta Vet Scand 7 [Suppl 16]:112
Stephenson LS, Pond WG, Nesheim MC, Krook LP, Crompton DWT (1980)Ascaris suum: nutrient absorption, growth and intestinal pathology in growing pigs experimentally infected with 15 day old larvae. Exp Parasitol 49:15–25
Underdahl NR, Kelley GW (1957) The enhancement of virus pneumonia of pigs by the migration ofAscaris suum larvae. J Am Vet Med Assoc 130:173–176
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Tjørnehøj, K., Eriksen, L., Aalbæk, B. et al. Interaction betweenAscaris suum andPasteurella multocida in the lungs of mice. Parasitol Res 78, 525–528 (1992). https://doi.org/10.1007/BF00931575
Accepted:
Issue Date:
DOI: https://doi.org/10.1007/BF00931575