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The electrical activity of single isolated smooth muscle cells

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Summary

  1. 1.

    Smooth mucle cells from the taenia coli of the guinea-pig have been grown in tissue culture.

  2. 2.

    Intracellular recordings from clumps of cells showed spontaneous spikes of variable height, associated with slow waves. Cells in clumps appeared to be electrotonically coupled to their neighbours.

  3. 3.

    Single isolated cells also generated spontaneous spikes and slow waves. Spikes from these cells were of nearly constant height.

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Authors and Affiliations

  1. Zoology Department, University of Melbourne, Parkville, Victoria, Australia

    Robert D. Purves, Gerda E. Mark & Geoffrey Burnstock

Authors
  1. Robert D. Purves
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  2. Gerda E. Mark
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  3. Geoffrey Burnstock
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Purves, R.D., Mark, G.E. & Burnstock, G. The electrical activity of single isolated smooth muscle cells. Pflugers Arch. 341, 325–330 (1973). https://doi.org/10.1007/BF01023674

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  • DOI: https://doi.org/10.1007/BF01023674

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