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Crystal structure of sulfamerazine

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Abstract

The structure of sulfamerazine, C11H12N4O2S, a very important sulfonamide drug, has been solved by direct methods with X-ray diffraction data collected using CuKα radiation. The crystals are orthorhombic, witha=9.145(1),b=11.704(1),c=22.884(2) Å and space groupPbca. The structure was refined with 2082 observed independent reflections, measured on a CAD-4 diffractometer, to a finalR value of 0.078. The molecule has similar conformational features to those observed in other sulfonamide drugs.

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Authors and Affiliations

  1. Department of Physics, Central College, Bangalore University, 560 001, Bangalore, India

    K. Ravindra Acharya & K. N. Kuchela

  2. New York State Department of Health, Roswell Park Memorial Institute, 14263, Buffalo, New York

    Gopinath Kartha

Authors
  1. K. Ravindra Acharya
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  2. K. N. Kuchela
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  3. Gopinath Kartha
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Ravindra Acharya, K., Kuchela, K.N. & Kartha, G. Crystal structure of sulfamerazine. Journal of Crystallographic and Spectroscopic Research 12, 369–376 (1982). https://doi.org/10.1007/BF01159053

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  • DOI: https://doi.org/10.1007/BF01159053

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