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Bioactivities and structural studies of withanolides fromWithania somnifera

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Four bioactive withanolides withalactone (1), withaoxylactone (2), quresimine-A (4β-hydroxy, 3β-methoxy-5β, 6β-epoxy-(22R)-witha-24-enolide) (3) and quresindne-B (4β, 27 dihydroxy-3β-methoxy-5β, 6β-epoxy-(22R)-witha-24-enolide (4) have been isolated from the herbs of Withania somnifera, Dunal (Solanaceae). The elucidation of their structures is based on extensive spectroscopic studies, such as1H-NMR, COSY-45°, HMBC, HMQC HOHAHA, E.I., FAB (+ ve), and HR MS, etc.

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Authors and Affiliations

  1. H. E. J. Research Institute of Chemistry, University of Karachi, 75274, Karachi, Pakistan

    S. Arshad Jamal, Samina Qureshi, Samina Noor Ali, M. Iqbal Choudhary &  Atta-Ur-Rahman

Authors
  1. S. Arshad Jamal
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  2. Samina Qureshi
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  3. Samina Noor Ali
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  4. M. Iqbal Choudhary
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  5. Atta-Ur-Rahman
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Published in Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1200–1213, September, 1995.

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Arshad Jamal, S., Qureshi, S., Noor Ali, S. et al. Bioactivities and structural studies of withanolides fromWithania somnifera . Chem Heterocycl Compd 31, 1047–1059 (1995). https://doi.org/10.1007/BF01165050

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  • DOI: https://doi.org/10.1007/BF01165050

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