Summary
Four indolic constituents of the pineal gland of rats exposed to light or dark conditions, respectively, were measured by HPLC. Animals that had had both superior cervical ganglia extirpated 8 days before pineal removal and analysis did not show the phasic changes in glandular content of melatonin, serotonin, 5-hydroxytryptophol or 5-hydroxyindoleacetic acid. On the other hand, unilaterally ganglionectomized rats displayed the types of response to photic stimulation seen in intact animals for all four compounds.
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Vassilieff, V.S., Sourkes, T.L. & Anderson, G.M. Superior cervical ganglionectomy: Effect on indolic compounds in rat pineal gland. J. Neural Transmission 55, 45–52 (1982). https://doi.org/10.1007/BF01243340
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DOI: https://doi.org/10.1007/BF01243340