Skip to main content
Log in

The pineal gland of the mole (Talpa europaea L.) II. Ultrastructural variations observed in the pinealocytes during different parts of the sexual cycle

  • Published:
Journal of Neural Transmission Aims and scope Submit manuscript

Summary

Changes of some ultrastructural parameters (paracrystalline structures, Golgi apparatus, secretory granules) in mole pinealocytes were quantitatively studied during the various phases of the sexual cycle. An increase in quantity of paracrystalline structures and of the Golgi apparatuses was demonstrated during the period of high sexual activity in male pinealocytes and during oestrus, gestation and lactation in female pinealocytes. Moreover, the appearance of vacuoles in female pinealocytes was observed during pro-oestrus.

These results seem to demonstrate close relationship between the endocrine activity of the hypophyseo-gonadal axis and the synthesis of some compounds by the pinealocytes.

No increase in the quantity of secretory granules was observed during the various phases of the sexual cycle studied.

Resume

L'évolution quantitative de quelques paramètres ultrastructuraux (structures paracristallines, appareils de Golgi, grains de sécrétion) des pinéalocytes de la taupe, a été suivie pendant les différentes phases du cycle sexuel. Cette étude a permis de montrer une augmentation du nombre des structures paracristallines et des appareils de Golgi pendant la phase de pleine activité sexuelle chez les mâles et pendant l'œstrus, la gestation et la lactation chez les femelles. De plus, l'apparition d'un phénomène de vacuolisation des pinéalocytes a été observée pendant le proestrus.

Ces résultats semblent démontrer d'étroites relations entre l'activité endocrine de l'axe adénohypophyse-gonades et l'accroissement des synthèses des pinéalocytes.

Aucune évolution du nombre de grains de sécrétion n'a été observée pendant les différentes phases du cycle sexuel.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Courner, T.: Étude sur le déterminisme des caractères sexuels secondaires chez quelques mammifères á l'activité testiculaire périodique. Arch. Biol. (Liège)37, 173–334 (1927).

    Google Scholar 

  • Costoff, A.: Ultrastructure of rat adenohypophysis. Correlations with function. New York-London: Academic Press. 1973.

    Google Scholar 

  • Cresti, M., E. Pacini, andC. Simoncioli: Uncommon paracrystalline structures formed in the endoplasmic reticulum of the integumentary cells ofDiplotaxis erucoïdes ovules. J. Ultrastruct. Res.49, 218–223 (1974).

    Google Scholar 

  • Deanesly, R.: Observations on the reproduction in the mole,Talpa europaea. In: Comparative Biology of Reproduction in Mammals (Rowlands T. W., ed.), pp. 387–401. London: Academic Press. 1966.

    Google Scholar 

  • Fawcett, D. W.: An Atlas of fine Structure. The Cell. Philadelphia: W. B. Saunders & Co. 1967.

    Google Scholar 

  • Girod, C., andP. Dubois: Étude ultrastructurale des cellules gonadotropes antéhypophysaires chez le Hamster doré (Mesocricetus auratus, Waterh.). J. Ultrastruct. Res.13, 212–232 (1965).

    PubMed  Google Scholar 

  • Glauert, A. M., andR. H. Glauert: Araldite as an embedding medium for electron microscopy. J. Biophys. Biochem. Cytol.4, 191–194 (1958).

    PubMed  Google Scholar 

  • Godet, R.: Recherches d'anatomie, d'embryologie normale et expérimentale sur l'appareil génital de la Taupe. Bull. Biol. Fr. Belg.83, 25–111 (1949).

    Google Scholar 

  • Godfrey, G., andP. Crowcrofl: The life of the mole. London: Museum Press. 1960.

    Google Scholar 

  • Gougeon, A.: Analyse histologique et histoenzymologique de l'interstitielle ovarienne chez deux insectivores Européens, la Taupe (Talpa europaea) et le Hérisson (Erinaceus enropaeus). Thèse IIIe cycle. Poitiers. 1972.

  • Gougeon, A.: Histoenzymologie de l'ovaire chez la Taupe. Evolution des potentialités stéroidogènes de l'interstitielle médullaire au cours du cycle sexuel annuel. Ann. Biol. Anim. Bioch. Biophys.14, 417–426 (1974).

    Google Scholar 

  • Harrison-Matthews, L.: The estrous cycle and intersexuality in the female mole. Proc. Zool. Soc. London1, 347–384 (1935).

    Google Scholar 

  • Herlant, M.: L'hypophyse de la Taupe au cours de la phase d'activité sexuelle. C.R. Acad. Sc.248, 1033–1036 (1959 a).

    Google Scholar 

  • Herlant, M.: Les modifications hypophysaires chez la Taupe au cours de la phase d'activité sexuelle. C.R. Acad. Sc.46, 347–354 (1959 b).

    Google Scholar 

  • Kitay, J. I., andM. D. Altscbule: The Pineal Gland. Commonwealth Fund Book. Cambridge, Mass.: Harvard Univ. Press. 1954.

    Google Scholar 

  • Pevet, P.: Étude ultrastructurale de l'épiphyse du Hérisson mâle. Evolution en fonction du cycle sexuel. Thèse IIIe cycle. Poitiers. 1972.

  • Pevet, P.: The pineal gland of the mole (Talpa europaea L.). The fine structure of the pinealocytes. Cell Tiss. Res.153, 277–292 (1974).

    Google Scholar 

  • Pevet, P.: Étude structurale et ultrastructurale de l'épiphyse du Hérisson (Erinaceus europaeus L.) mâle. Evolution en fonction du cycle sexuel. In: Vme entretiens de Chizé. Problèmes endocriniens chez les mammifères sauvages —Aspects métaboliques en écophysiologique. (In press, 1975 a.)

  • Pevet, P.: Vacuolated pinealocytes in the hedgehog (Erinaceus europaeus L.) and the mole (Talpa europaea L.). Cell Tiss. Res. (In press. 1975 b.)

  • Pevet, P., andM. Saboureau: Modifications ultrastructurales dans l'épiphyse du Hérisson mâle au cours du repos sexuel. Gen. Comp. Endocr.18, 615–616 (1972).

    Google Scholar 

  • Pevet, P., andM. Saboureau: L'épiphyse du Hérisson (Erinaceus europaeus L.) mâle. I. Leś pinéalocytes et leurs variations ultrastructurales considérées au cours du cycle sexuel. Z. Zellforsch.143, 367–385 (1973).

    PubMed  Google Scholar 

  • Peyre, A.: Cycles génitaux et corrélation hypophyso-génitales chez trois Insectivores Européens. In: Cycles Génitaux Saisonniers de Mammifères Sauvages, pp. 133–149. Paris: Masson & Cie. 1968.

    Google Scholar 

  • Pieters, A., andM. Herlant: Modifications saisonnières des cellules à prolactine dans l'antéhypophyse de la Taupe mâle. C.R. Acad. Sc.274, 3002–3006 (1972).

    Google Scholar 

  • Reiter, R. J.: The effect of pineal grafts, pinealectomy and denervation of the pineal gland on the reproductive organs of male hamster. Neuro-endocrinol.2, 138–146 (1967).

    Google Scholar 

  • Reiter, R. J.: Morphological studies on the reproductive organs of blinded male hamster and the effect of pinealectomy and superior cervical ganglionectomy. Anat. Rec.160, 13–24 (1968).

    PubMed  Google Scholar 

  • Reiter, R. J.: Pineal function in long term blinded male and female golden hamster. Gen. Comp. Endocr.12, 460–468 (1969).

    PubMed  Google Scholar 

  • Reiter, R. J.: Pineal control of a seasonal reproductive rhythm in male golden hamsters exposed to natural daylight and temperature. Endocrinology92, 423–430 (1973).

    PubMed  Google Scholar 

  • Reynolds, E. S.: The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J. Cell Biol.17, 208–212 (1963).

    PubMed  Google Scholar 

  • Smith, A. R.: Conditions influencing the serotonin and tryptophan metabolism in the epiphysis cerebri of the rabbit: A fluorescence histochemical microchemical and electrophoretic study. Thesis, Med. Fac., Amsterdam. 1972.

    Google Scholar 

  • Smith, A. R., J. F. Jongkind, andJ. Ariëns Kappers: Distribution and quantification of serotonin-containing and autofluorescent cells in the rabbit pineal organ. Gen. Comp. End.18, 364–371 (1972).

    Google Scholar 

  • Smith, A. R., P. Pevet, andL. van de Kar: Effect of gonadotropic hormones on the rat pineal gland: A fluorescence histochemical and biochemical study. J. Neural Transm. (in press, 1975).

  • Tandler, J., andS. Grosz: Über den Saisondimorphismus des Maulwurfhodens. Arch. Enrw. mech. Org.35, 132–134 (1912).

    Google Scholar 

  • Venable, J. M., andW. Coggeshall: Simplified lead stain for use in electron microscopy. J. Cell Biol.25, 407–408 (1965).

    PubMed  Google Scholar 

  • Vivien, J. H.: Signes de stimulation des activités sécrétoires des pinéalocytes chez la couleuvreTropidonotus natrix L. traitée par des principes gonadotropes.

  • Wurtman, R. J., J. Axelrod, andD. E. Kelly: The Pineal. New York-London: Academic Press. 1968.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

In gratitude and with admiration this paper is dedicated to Professor Dr. J. Ariëns Kappers.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pevet, P., Smith, A.R. The pineal gland of the mole (Talpa europaea L.) II. Ultrastructural variations observed in the pinealocytes during different parts of the sexual cycle. J. Neural Transmission 36, 227–248 (1975). https://doi.org/10.1007/BF01253128

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01253128

Key words

Navigation