Skip to main content
Log in

Morphometry of the parahippocampal gyrus in schizophrenics and controls. Some anatomical considerations

  • Short Communication
  • Published:
Journal of Neural Transmission / General Section JNT Aims and scope Submit manuscript

Summary

Volumetry of the parahippocampal gyrus was performed applying stereological methods. No difference was found comparing 18 schizophrenic brains with 18 sex- and age-matched controls. Variable sulcal pattern may contribute to inconsistency with previous findings.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Bogerts B, Meertz E, Schönfeldt-Bausch R (1985) Basal ganglia and limbic system pathology in schizophrenia. A morphometric study of brain volume and shrinkage. Arch Gen Psychiatry 42: 784–791

    PubMed  Google Scholar 

  • Braak H (1980) Architectonics of the human telencephalic cortex. In: Braitenberg V, Barlow HB, Bizzi E, Grüsser OJ, van der Loos H (eds) Studies of brain function, vol. 4. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Brown R, Colter N, Corsellis JAN, Crow TJ, Frith CD, Jagoe R, Johnstone EC, Marsh L (1986) Postmortem evidence of structural brain changes in schizophrenia. Differences in brain weight, temporal horn area, and parahippocampal gyrus compared with affective disorder. Arch Gen Psychiatry 43: 36–42

    PubMed  Google Scholar 

  • Colter N, Battal S, Crow TJ, Johnstone EC, Brown R, Bruton C (1987) White matter reduction in the parahippocampal gyrus of patients with schizophrenia. Arch Gen Psychiatry 44: 1023

    Google Scholar 

  • Economo C von, Koskinas GN (1925) Die Cytoarchitektonik der Hirnrinde des erwachsenen Menschen. Springer, Wien Berlin

    Google Scholar 

  • Falkai P, Bogerts B, Rozumek M (1988) Limbic pathology in schizophrenia: the entorhinal region-a morphometric study. Biol Psychiatry 24: 515–521

    PubMed  Google Scholar 

  • Gundersen HJG, Bendtsen TF, Korbo L, Marcussen N, Moller A, Nielsen K, Nyengaard JR, Pakkenberg B, Sorensen FB, Vesterby A, West MJ (1988) Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96: 379–394

    PubMed  Google Scholar 

  • Jakob H (1979) Die Picksche Krankheit: Eine neuropathologisch-anatomisch-klinische Studie. Springer, Berlin Heidelberg New York

    Google Scholar 

  • Jakob H, Beckmann H (1986) Prenatal developmental disturbances in the limbic allocortex in schizophrenics. J Neural Transm 65: 303–326

    PubMed  Google Scholar 

  • Kemper T (1984) Neuroanatomical and neuropathological changes in normal aging and dementia. In: Albert ML (ed) Clinical neurology of aging. Oxford University Press, New York, pp 9–52

    Google Scholar 

  • Meldrum BS, Corsellis JAN (1984) Epilepsy. In: Adams JH, Corsellis JAN, Duchen LW (eds) Greenfield's neuropathology. Edward Arnold, London, pp 921–950

    Google Scholar 

  • Mesulam MM (1985) Principles of behavioral neurology. FA Davis, Philadelphia

    Google Scholar 

  • Naidich TP, Daniels DL, Haughton VM, Williams A, Pojunas K, Palacios E (1987) Hippocampal formation and related structures of the limbic lobe: anatomic-MR correlation. Part I. Surface and coronal sections. Radiology 162: 747–754

    PubMed  Google Scholar 

  • Press GA, Amaral DG, Squire LR (1989) Hippocampal abnormalities in amnesic patients revealed by high-resolution magnetic resonance imaging. Nature 341: 54–57

    PubMed  Google Scholar 

  • Retzius G (1896) Das Menschenhirn. Studien in der makroskopischen Morphologie. Norstedt & Söner, Stockholm

    Google Scholar 

  • Van Hoesen GW (1982) The parahippocampal gyrus. New observations regarding its cortical connections in the monkey. TINS 5: 345–350

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Supported by a grant from the DFG (Be 602/6-1). Presented in part at the 8th World Congress of Psychiatry, Athens, Greece, October 12–19, 1989.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Heckers, S., Heinsen, H., Heinsen, Y. et al. Morphometry of the parahippocampal gyrus in schizophrenics and controls. Some anatomical considerations. J. Neural Transmission 80, 151–155 (1990). https://doi.org/10.1007/BF01257080

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01257080

Keywords

Navigation