Summary
Directly under the ependyma, and between the ependymal cells, there are basement membranes which form labyrinths connecting with the perivascular basement membranes of the subependymal vessels. The basement membranes exhibit differences in form, position, and distribution, and they can be distended by fluid absorption into large lacunae. The membranes can be identified as glycoprotein and glylcolipid substances.
Electron microscopic studies have shown the differences between the basement membrane labyrinths of the human, the rabbit and the rat. In the human, the labyrinths contain isolated collagen fibrils.
Basement membranes generally line all connective tissue spaces and form their interstitial borders. From this point of view, the subependymal basement membrane labyrinths can be seen as interstitial spaces near the ventricles, forming pathways between the ependyma and the subependymal capillaries or postcapillary veins.
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References
Bering, E. A. Jr., The cerebrospinal fluid circulation. In: Cerebrospinal fluid and the regulation of ventilation. The proceedings of a symposium held at the Downstate Medical Center, State University of New York (Ch. McC. Brooks, F. F. Kao, and B. B. Lloyd ed.). Oxford: Blackwell Scientific Publications. 1965.
—, and O. Sato, Hydrocephalus: changes in formation and absorption of cerebrospinal fluid within the cerebral ventricles. J. Neurosurg.20 (1963), 1050–1063.
Booz, K. H., and U. Desaga, Sub- und interependymale Basalmembranlabyrinthe am Ventrikelsystem und Zentralkanal der weißen Ratte. Anat. Anz.135, Erg.-Bd. (1973), 609–612.
Brightman, M. W., The distribution within the brain of ferritin injected into cerebrospinal fluid compartments. I. Ependymal distribution. J. Cell. Biol.26 (1965), 99–123.
Cushing, H., Studies on the cerebrospinal fluid. J. med. Res.31 (1914), 1–49.
Dandy, W. E., Where is cerebrospinal fluid absorbed? J. Amer. med. Ass.92 (1929), 2012–2014.
De Rougemont, J., A. Ames III, F. B. Nesbett, and H. F. Hofmann, Fluid formed by choroid plexus. J. Neurophysiol.23 (1960), 485–495.
Desaga, U., Licht- und elektronenmikroskopischer Nachweis subependymaler Basalmembranlabyrinthe im III. Ventrikel der Ratte. Z. mikr. -anat. Forsch.85 (1972), 50–54.
—, Form und Verteilung subependymaler Basalmembranlabyrinthe am Ventrikelsystem der Ratte. Z. Zellforsch.132 (1972), 553–562.
Jacobi, W., and G. Magnus, Gefäß und Liquorstudien am Hirn des lebenden Hundes. Arch. Psychiat. Nerv. Krankh.73 (1925), 126–138.
Leonhardt, H., Subependymale Basalmembranlabyrinthe im Hinterhorn des Seitenventrikels des Kaninchengehirns. Zur Frage des Liquorabflusses. Z. Zellforsch.105 (1970), 595–604.
—, Über die topographische Verteilung der subependymalen Basalmembranlabyrinthe im Ventrikelsystem des Kaninchengehirns. Z. Zellforsch.127 (1972), 392–406.
—, Über elektronenmikroskopische Unterschiede zwischen den subependymalen Basalmembranlabyrinthen von Mensch, Ratte und Kaninchen. Anat. Anz.135, Erg.-Bd. (1973), 605–607.
Pollay, M., and H. Davson, The passage of certain substances out of the cerebrospinal fluid. Brain86 (1963), 137–150.
Specht, W., Färben mit Aldehydthionin. Eine Methode für den topochemischen Nachweis von Sulfonsäuren und Aldehyden. 65. Vers. Anat. Ges., Würzburg 1970.
Vollrath, L., Über Bau und Funktion von Basalmembranen. Dtsch. med. Wschr.93 (1968), 360–365.
Welch, K., Secretion of cerebrospinal fluid by choroid plexus of the rabbit. Amer. J. Physiol.205 (1963), 617–624.
Westergaard, E., The lateral ventricles and the ventricular walls. An anatomical, histological and electron-microscopic investigation on mice, rats, hamsters, guinea-pigs and rabbits. I kommission hos Andelsbogtrykkeriet i Odense, 1970.
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This investigation was supported by a grant from the “Deutsche Forschungsgemeinschaft”.
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Leonhardt, H., Desaga, U. Recent observations on ependyma and subependymal basement membranes. Acta neurochir 31, 153–159 (1975). https://doi.org/10.1007/BF01406287
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DOI: https://doi.org/10.1007/BF01406287