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The clinical importance of erythrocyte deformability, a hemorrheological parameter

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Summary

Hemorrheology, the science of the flow behavior of blood, has become increasingly important in clinical situations. The rheology of blood is dependent on its viscosity, which in turn is influenced by plasma viscosity, hematocrit, erythrocyte aggregation, and erythrocyte deformability. In recent years it has become apparent that the shape and elasticity of erythrocytes may be important in explaining the etiology of certain pathological situations. Thus, clinicians have become increasingly interested in hemorrheology in general and erythrocyte deformability in particular. In the course of time, many clinical studies have been performed, but no concise review has thus far been published. This article encompasses a review of the clinically based literature on this subject.

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  1. Department of Anesthesiology, Academic Medical Center, University Hospital of the University of Amsterdam, Meibergdreef 9, 1105, AZ Amsterdam, The Netherlands

    F. Ch. Mokken, M. Kedaria & Ch. P. Henny

  2. Department of Internal Medicine, Division of Hemorrheology, Academic Medical Center, University Hospital of the University of Amsterdam, Meibergdreef 9, 1105, AZ Amsterdam, The Netherlands

    M. R. Hardeman

  3. Department of Anesthesia, University Hospital, London, Ontario, Canada

    A. W. Gelb

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Mokken, F.C., Kedaria, M., Henny, C.P. et al. The clinical importance of erythrocyte deformability, a hemorrheological parameter. Ann Hematol 64, 113–122 (1992). https://doi.org/10.1007/BF01697397

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