Summary
Mitochondria and bacteria possess protein synthesizing machineries which are similar in many respects. The regulation of gene expression in mitochondria is unknown. We, therefore, tried to use a well-established prokaryotic regulatory system for the exploration of mitochondrial gene regulation. DNA of the bacterial virus can be used as a template for gene expression in a mitochondrialin vitro system. The gene directed enzyme synthesis in the mitochondrial system is the basis for a study of regulation in mitochondrial protein synthesis.
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Herrlich, P., Ponta, H., Richter, D. et al. Gene expression in mitochondria and bacteria. Mol Cell Biochem 14, 143–149 (1977). https://doi.org/10.1007/BF01734178
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DOI: https://doi.org/10.1007/BF01734178