Abstract
Chemical studies of the Caribbean red algaVidalia obtusaloba have resulted in the isolation of two new bromophenolic metabolites, vidalols A and B (1, 2). The new compounds were discovered as part of an organized effort to isolate new naturally-occurring anti-inflammatory agents with a focus upon those which may function through the inhibition of phospholipase A2.
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References
Fenical, W., J. nat. Prod.50 (1987) 1001.
Mayer, A. M. S., deCarvalho, M. S., Jacobs, R. S., Paul, V. J., and Fenical, W., Planta Medica, submitted, 1991.
NMR data for vidalol A (1):13C NMR (CDCl3) δ 134.2 (C, C-1), 115.1 (C, C-2), 113.8 (C, C-3), 143.8 (C, C-4), 145.7 (C, C-5), 116.4 (C, C-6), 31.9 (CH2, C-7), 107.2 (C, C-1′), 154.4 (C, C-2′), 90.8 (C, C-3′), 157.1 (C, C-4′), 96.4 (CH, C-5′), 154.3 (C, C-6′); proton NMR data are in the body.
Kurata, K., and Amiya, T., Chem. Lett. (1977) 1435.
Wehrli, F. W., and Wirthlin, T., Interpretation of Carbon-13 NMR Spectra. Heyden and Sons Ltd. London 1978.
Chevolot-Magueur, A.-M., Cave, A., Potier, P., Teste, J., Chiaroni, A., and Riche, C., Phytochemistry15 (1976) 767.
NMR data for vidalol B (2):13C NMR (CDCl3) δ 155.5 (1C), 152.8 (2C), 146.0 (2C), 143.4 (2C), 134.0 (2C), 116.7 (2C), 115.3 (2C), 114.2 (2C), 109.1 (2C), 93.7 (1C), 32.6 (2C); proton NMR data are in the body.
Faulkner, D. J., Nat. Prod. Rep.1 (1984) 251.
Sun, H. H., Paul, V. J., and Fenical, W., Phytochemistry11 (1983) 743; Colon, M., Guevara, P., Gerwick, W. H., and Ballantine, D., J. Nat. Prod.50 (1987) 368; Carte, B. K., Troupe, N., Chan, J. A., Westley, J. W., and Faulkner, D. J., Phytochemistry28 (1989) 2917.
Hodgkin, J. H., Craigie, J. S., and McInnes, A. G., Can. J. Chem.44 (1966) 74.
Hay, M. E., Duffy, J. E., and Fenical, W., Proc. 6th. Int. Coral Reef Symp.3 (1988) 43.
Gerwick, W. H., Fenical, W., Fritsch, N., and Clardy, J., Tetrahedron Lett. (1979) 145.
O'Brien, E. T., Asai, D. J., Groweiss, A., Lipshutz, B. H., Fenical, W., Jacobs, R. S., and Wilson, L., J. med. Chem.29 (1986) 1951.
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Wiemer, D.F., Idler, D.D. & Fenical, W. Vidalols A and B, new anti-inflammatory bromophenols from the Caribbean marine red algaVidalia obtusaloba. Experientia 47, 851–853 (1991). https://doi.org/10.1007/BF01922471
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DOI: https://doi.org/10.1007/BF01922471