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10-Methoxyergoline derivatives asα-adrenergic blocking agents

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Riassunto

Vengono descritte le attività adrenolitiche di una nuova classe di derivati dell'ergolina di formula generale IV. Uno di questi composti (No. 20) è stato esaminato su diversi reattivi biologici che hanno messo in luce la sua attività vasodilatatrice e adrenolitica e l'assenza di attività indesiderate tipiche degli alcaloidi dell'Ergot.

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Authors and Affiliations

  1. Department of Chemistry and Department of Pharmacology, Farmitalia, Istituto Ricerche, I-20146, Milano, Italy

    G. Arcari, L. Bernardi, G. Bosisio, S. Coda, G. B. Fregnan & A. H. Glässer

Authors
  1. G. Arcari
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  2. L. Bernardi
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  3. G. Bosisio
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  4. S. Coda
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  5. G. B. Fregnan
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  6. A. H. Glässer
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Additional information

Ergoline derivatives. Note X, Note IX:W. Barbieri, L. Bernardi, G. Bosisio andA. Temperilli, Tetrahedron25, 2401 (1969).

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Arcari, G., Bernardi, L., Bosisio, G. et al. 10-Methoxyergoline derivatives asα-adrenergic blocking agents. Experientia 28, 819–820 (1972). https://doi.org/10.1007/BF01923151

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