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Blockade of the hydrosmotic effect of vasopressin by cytochalasin B

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Résumé

La cytochalasine B dissocie les effets hydrosmotique et natriférique de la Pitressine sur la vessie de crapaud, en bloquant le transport d'eau sans pour autant modifier la stimulation du transport de sodium. Les interactions possibles entre le macrolide, les microfilaments et les altérations de perméabilité sont discutées.

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Literatur

  1. S. B. Carter, Endeavour31, 77 (1972).

    CAS  Google Scholar 

  2. W. Rothweiler andCh. Tamm, Experientia22, 750 (1966).

    Article  CAS  Google Scholar 

  3. S. B. Carter, Nature213, 261 (1967).

    Article  CAS  Google Scholar 

  4. N. K. Wessels, B. S. Spooner, J. F. Ash, M. O. Bradley, M. A. Luduena, E. L. Taylor, J. T. Wrenn andK. M. Yamada, Science171, 135 (1971).

    Article  Google Scholar 

  5. L. Orci, K. H. Gabbay andW. J. Malaisse, Science175, 1128 (1972).

    Article  CAS  Google Scholar 

  6. H. Holtzer andJ. W. Sanger, Devel. Biol.27, 444 (1972).

    CAS  Google Scholar 

  7. R. C. de Sousa andA. Grosso, Experientia29, 1097 (1973).

    Article  Google Scholar 

  8. M. Rüphi, R. C. de Sousa, E. Favrod-Coune andJ. M. Posternak, Experientia28, 1391 (1972).

    Article  Google Scholar 

  9. Studies on water flow across frog skin were discontinued due to the wide variability of hydrosmotic responses in this epithelium.

  10. R. F. Kletzien andJ. F. Perdue, J. biol. Chem.248, 711 (1973).

    Article  CAS  Google Scholar 

  11. P. G. W. Plagemann andR. D. Estensen, J. Cell Biol.55, 179 (1972).

    Article  CAS  Google Scholar 

  12. L. D. Peachey andH. Rasmussen, J. Biophys. biochem. Cytol.10, 529 (1961).

    Article  CAS  Google Scholar 

  13. S. K. Masur, E. Holtzman, I. L. Schwartz andR. Walter, J. Cell Biol.49, 582 (1971).

    Article  CAS  Google Scholar 

  14. S. K. Masur, E. Holtzman andR. Walter, J. Cell Biol.52, 211 (1972).

    Article  CAS  Google Scholar 

  15. B. P. Croker Jr, andC. C. Tisher, Kidney International1, 145 (1972).

    Article  CAS  Google Scholar 

  16. A. Taylor, M. Mamelak, E. Reaven andR. Maffly, Science181, 347 (1973).

    Article  CAS  Google Scholar 

  17. These authors reported also that effects of microtubular agents on toad bladder are similar to those of CB, an observation consistent with results from our laboratory. We noticed, however, that colchicine and strychnine do not alter sodium transport if added to the internal side of the skin, while addition to the external side is followed by a stimulation of sodium transport very similar to that observed with DPH7 and lanthanides.

  18. R. C. de Sousa, J. Marguerat andA. Grosso, Experientia29, 749 (1973).

    Article  Google Scholar 

  19. We thank Dr.G. W. G. Sharp for careful reading of the manuscript, MissD. Kaelin for technical assistance, and Sandoz Ltd for a generous gift of Syntocinon.

  20. Supported by SNF grants Nos 3.567.71 and 3.8080.72.

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Author notes

  1. R. C. de Sousa

    Present address: Department of Medicine, University of Geneva, Geneva, Switzerland

  2. A. Grosso

    Present address: Department of Physiology, University of Geneva, Geneva, Switzerland

  3. C. Rufener

    Present address: Department of Histology, University of Geneva, Geneva, Switzerland

Authors and Affiliations

  1. Département de Physiologie de l'Université Ecole de Médecine, 1211, Genève 4, Switzerland

    R. C. de Sousa, A. Grosso & C. Rufener

Authors
  1. R. C. de Sousa
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  2. A. Grosso
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  3. C. Rufener
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de Sousa, R.C., Grosso, A. & Rufener, C. Blockade of the hydrosmotic effect of vasopressin by cytochalasin B. Experientia 30, 175–177 (1974). https://doi.org/10.1007/BF01927718

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  • DOI: https://doi.org/10.1007/BF01927718

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