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The role of sialic acid in determining the life-span of circulating cells and glycoproteins

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Summary

The role of sialic acid in determining the life of circulating cells and glycoproteins is reviewed and an attempt is made to assess its real importance and to interpret the desialylation pathway. An overall view of factors, including desialylated glycoprotein fragments, that may regulate hepatic synthesis of glycoproteins is presented.

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  1. Istituto di Fisiologia Generale, Università di Siena, I-53100, Siena, Italy

    V. Bocci

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Acknowledgments. The author wishes to thank Drs.A. Viti andG. P. Pessina for helpful discussion and comments.

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Bocci, V. The role of sialic acid in determining the life-span of circulating cells and glycoproteins. Experientia 32, 135–140 (1976). https://doi.org/10.1007/BF01937727

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