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Regulation of enzymes of ethanol metabolism in yeast (Rhodotorula gracilis)

  • Specialia Chimica, Biochimica
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Summary

The three enzymes of ethanol metabolism alcohol dehydrogenase, aldehyde dehydrogenase and acetyl-CoA synthetase in the obligate aerobic yeastRhodotorula gracilis are repressed by glucose and induced by C2 metabolic fuels with a regulatory pattern indicating a correlation in the control mechanisms. To try an identification of the molecular signals involved in the transmission of the inducing stimulus, experiments were carried out by blocking with 2 mM pyrazole the ethanol ↼ ↼ acetaldehyde metabolic step. Results indicate that ethanol is not specifically required as a molecular signal for induction.

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Authors and Affiliations

  1. Department of General Physiology and Biochemistry, University of Milan, 50, Via Saldini, I-20133, Milano, Italy

    G. M. Hanozet, M. Simonetta, D. Barisio & A. Guerritore

Authors
  1. G. M. Hanozet
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  2. M. Simonetta
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  3. D. Barisio
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  4. A. Guerritore
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Additional information

This work was supported by a grant from the Italian Consiglio Nazionale delle Ricerche.

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Hanozet, G.M., Simonetta, M., Barisio, D. et al. Regulation of enzymes of ethanol metabolism in yeast (Rhodotorula gracilis). Experientia 32, 1246–1249 (1976). https://doi.org/10.1007/BF01953073

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  • DOI: https://doi.org/10.1007/BF01953073

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