Summary
The effective unstirred layer thickness in the rat jejunum perfused in vivo amounts to at least 530 μm. This value has been estimated from the absorption increase ofl-phenylalanine due to better mixing of the luminal solution by air bubbles.
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References
J. Dainty andC. R. House, J. Physiol., Lond.182, 66 (1966).
A. P. Smulders andE. M. Wright, J. Membr. Biol.5, 297 (1971).
V. L. Sallee andJ. M. Dietschy, J. Lipid Res.14, 475 (1973).
R. B. Fisher, inOxygen in the Animal Organism (Eds.F. Dickens andE. Neil; Pergamon, Oxford (1964), p. 339.
D. Winne, Biochim. biophys. Acta,298, 27 (1973).
F. A. Wilson andJ. M. Dietschy, Biochim. biophys. Acta363, 112 (1974).
M. C. Dugas, K. Ramaswamy andR. K. Crane, Biochim. biophys. Acta382, 576 (1975).
K. Kakemi, T. Arita, R. Hori, R. Konishi, K. Nishimura, H. Matsui andT. Nishimura, Chem. Pharm. Bull., Tokyo17, 255 (19690.
A. Suzuki, W. I. Higuchi andN.F.H. Ho, J. pharm. Sci.59, 644 (1970).
A. Suzuki, W. I. Higuchi andN.F.H. Ho, J. pharm. Sci59, 651 (1970).
E. G. Lovering andD. B. Black, J. pharm. Sci.63, 1399 (1974).
J. M. Diamond, J. Physiol., Lond.183, 83 (1966).
H. Westergaard andJ. M. Dietschy, J. clin. Invest.54, 718 (1974).
B. E. Lukie, H. Westergaard andJ. M. Dietschy, Gastroenterology67, 652 (1974).
R. B. Fisher andM. L. G. Gardner, J. Physiol., Lond.241, 211 (1974).
H. Ochsenfahrt andD. Winne, Naunyn-Schmiedebergs Arch. Pharmak.264, 55 (1969).
D. Winne andJ. Remischovsky, Naunyn-Schmiedebergs Arch. Pharmak.268, 392 (1971).
C. R. Wilke, Chem. Eng. Progr.45, 218 (1949).
L. G. Longsworth, J. Am. chem. Soc.75, 5705 (1953).
E. L. Jervis andD. H. Smyth, J. Physiol., Lond.149, 433 (1959).
A. K. Rider, H. P. Schedl, G. Nokes andS. Shining, J. gen. Physiol.50, 1173 (1967).
H. Förster andB. Menzel, Z. Ernährungswiss.11, 24 (1972).
F. Rey, F. Drillet, J. Schmidt andJ. Rey, Gastroenterology66, 79 (1974).
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Winne, D. Unstirred layer thickness in perfused rat jejunum in vivo. Experientia 32, 1278–1279 (1976). https://doi.org/10.1007/BF01953092
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DOI: https://doi.org/10.1007/BF01953092