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Biogenic amine participation in histamine stimulation of ACTH release

  • Histamine and Kinins
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Abstract

Evidence of some interaction of adrenergic and serotonergic pathways with histamine induction of ACTH release is presented. Phentolamine, propranolol andp-chlorophenylalanine augmented this endocrine response to histamine, while the dopaminergic antagonist haloperidol had no effect.

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References

  1. P.A. Nasmyth,The effect of chlorpromazine on adrenocortical activity in stress, Br. J. Pharmac.10, 336–339 (1955).

    Google Scholar 

  2. M.A. Reilly andE.B. Sigg,Suppression of histamine-induced adrenocorticotropic hormone release by antihistamines and antidepressants, J. Pharmac. exp. Ther.222, 583–588 (1982).

    Google Scholar 

  3. W.D. Gray andP.L. Munson,The rapidity of the adrenocorticotropic response of the pituitary to the intravenous administration of histamine, Endocrinol.48, 471–481 (1951).

    Google Scholar 

  4. J. Fuche andG. Kahlson,Histamine as a stimulant to the anterior pituitary gland as judged by the lymphopenic response in normal and hypophysectomized rabbits, Acta physiol. scand.39, 327–347 (1957).

    Google Scholar 

  5. G. Kahlson andE. Rosengren, Formation and metabolism of histamine in the brain. InBiogenesis and Physiology of Histamine, pp. 184–192. Edward Arnold, London 1971.

    Google Scholar 

  6. J.A. Zivin andJ.J. Bartko,Statistics for disinterested scientists, Life Sci.18, 15–26 (1976).

    Google Scholar 

  7. A.L. Edwards, Multiple comparisons in the analysis of variance. InExperimental Design in Psychological Research, pp. 136–157. Holt, Rinehart and Winston, New York 1963.

    Google Scholar 

  8. R.W. Fuller,Pharmacology of central serotonin neurons, Ann. Rev. Pharmac. Toxicol.20, 111–127 (1980).

    Google Scholar 

  9. R.I. Weiner andW.F. Ganong,Role of brain monoamines and histamine in regulation of anterior pituitary secretion, Physiol. Rev.58, 905–976 (1978).

    Google Scholar 

  10. P. Naranjo andE.B. Naranjo,Pressor effect of histamine in the rabbit, J. Pharmac. exp. Ther.123, 16–21 (1958).

    Google Scholar 

  11. R.L. Noble andJ.B. Collip,The response of normal, hypophysectomized and adrenalectomized rats to histamine administration, Am. J. Physiol.133, 623–633 (1941).

    Google Scholar 

  12. B.N. Halpern, B. Benacerraf andM. Briot,Potentiation by adrenaline of protective effect of cortisone on histamine toxicity in adrenalectomized mice, Proc. Soc. exp. Biol. Med.79, 37–39 (1952).

    Google Scholar 

  13. P. Naranjo, Toxicity of histamine: lethal doses. InHandbook of Experimental Pharmacology, vol. 18, Part I, pp. 179–201 (Ed.M. Rocha e Silva). Springer, Berlin 1966.

    Google Scholar 

  14. J. Bugajski andZ. Janusz,Lipolytic responses induced by intracerebroventricular administration of histamine in the rat, Agents and Actions11, 147–150 (1981).

    Google Scholar 

  15. W.F. Ganong, Control of adrenocorticotropin and melanocyte-stimulating hormone secretion. InThe Hypothalamus, pp. 313–333 (EdsL. Martini, M. Motta andF. Fraschini). Academic Press, New York 1970.

    Google Scholar 

  16. T.J. Keeton andW.A. Pettinger,The dominance of adrenergic mechanisms in mediating hypotensive drug-induced renin release in the conscious rat, J. Pharmac. exp. Ther.208, 303–309 (1979).

    Google Scholar 

  17. R.B. Messing, D.J. Pettibone, N. Kaufman andL.D. Lytle,Behavioral effects of serotonin neurotoxins: an overview, Ann. N.Y. Acad. Sci.305, 480–496 (1978).

    Google Scholar 

  18. S. Fock andS. Mense,Excitatory effects of 5-hydroxytryptamine, histamine, and potassium ions on muscular group IV afferent units: a comparison with bradykinin, Brain Res.105, 459–469 (1976).

    Google Scholar 

  19. M.T. Jones, Control of corticotropin (ACTH) secretion. InThe Endocrine Hypothalamus, pp. 385–419 (EdsS.L. Jeffcoate andJ.S.M. Hutchison). Academic Press, London 1978.

    Google Scholar 

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Reilly, M.A. Biogenic amine participation in histamine stimulation of ACTH release. Agents and Actions 14, 630–632 (1984). https://doi.org/10.1007/BF01978898

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