Abstract
Twenty rats underwent a crush injury to their sciatic nerve, followed immediately by a single low-power coherent or non-coherent irradiation administered transcutaneously on the projection of an injured peripheral nerve. Five wavelengths were tested: 632.8, 660, 830, 880 and 950 nm. The electrical activities of the crushed nerve, immediately after irradiation and on the following first, third and seventh day post-crush, were compared to the precrush activity. The results indicate that energy at the wavelength of 632.8 nm (CW He-Ne laser), delivered transcutaneously (10 J cm−2 at each point) along the projections of the nerve, prevents the drop in the functional nerve activity as measured by the combined action potential (AP) after crush injury. Other wavelengths were either less effective (660 nm) or totally ineffective under the same conditions. The beneficial effects were temporary and lasted only one day after injury and the single irradiation session.
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Anderson RR, Parrish JA. The optics of laser therapy on wound contraction and cellularity in mice.Laser Med Sci 1986,1:125–30
Dyson M, Young S. Effect of laser therapy on wound contraction and cellularity in mice.Laser Med Sci 1986,1:125–30
Kana JS, Haina D, Waidelich W. Effect of low-power density laser radiation on healing of open skin wounds in rats.Arch Surg 1981,116:293–6
Karu TI. Photobiological fundamentals of low-power laser therapy.IEEE J Quant Elec 1987,23:1703–17
Letokhov VS. Laser biology and medicine.Nature 1985,316:325–9
Mester E, Spiry T, Szende B, Tota JG. Effect of laser rays on wound healing.Am J Surg 1971,122:532–5
Mester E, Mester AF, Mester A. The biomedical effects of laser application.Laser Surg Med 1985,5:31–9
Nissan M. Rochkind S, Ringel M. Strain gauged hemostatic forceps for clinical and experimental use.Med Biol Eng Comput 1988,26:448–50
Olson JE, Schimmerling W, Tobias CA. Laser action spectrum of reduced excitability in nerve cells.Brain Res 1981,204:436–40
Oyamada Y, Izu S. Application of low-energy laser in chronic rheumatic arthritis and related rheumatoid diseases.Proc 6th Cong Int Soc Laser Surg Med 13–18 October 1985, Israel
Ribari O. The stimulating effect of low-power laser rays: experimental examinations in otorhinolaryngology.Rev. Laryngol 1981,102:531–33
Rochkind S. Stimulation effect laser energy on the regeneration of traumatically injured peripheral nerves. Morphogenesis and regeneration 1978,73:48–50
Rochkind S, Nissan M, Razon N et al. Electrophysiological effect of He-Ne laser on normal and injured sciatic nerve in the rat.Acta Neurochirgica 1986,83:125–30
Rochkind S, Barr-Nea L, Razon N et al. Stimulatory effect of He-Ne low dose laser on injured sciatic nerves of rats.Neurosurgery 1987a,20:843–7
Rochkind S, Nissan M, Barr-Nea L et al. Response of peripheral nerve to He-Ne laser: Experimental studies.Laser Surg Med 1987b,7:441–3
Rochkind S, Lubart B, Nissan M, Barr-Nea L. Low energy laser irradiation and the nervous system: Method and Results.SPIE Vol. 907. In: Joffe SN, Atsumi K (eds)Laser Surgery: Characterization and Therapeutics, 1988a:100–6
Rochkind S, Barr-Nea L, Bartal A et al. New Methods of treatment of severely injured sciatic nerve and spinal cord.Acta Neurochirgica (Suppl) 1988b,43:91–3
Rochkind S, Nissan M, Lubart R, Bartal A. The in-vivo nerve response to direct low-energy laser irradiation.Acta Neurochirgica 1988c,94:74–7
Rochkind S, Rousso M, Nissan M et al. Systemic effect of low-power laser irradiation on the peripheral and central nervous system, cutaneous wounds and burns.Laser Surg Med 1989,9:174–82
Walker J. Relief from chronic pain by low-energy laser irradiation.Neuroscience Letters 1983,43:339–44
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Rochkind, S., Nissan, M. & Lubart, A. A single transcutaneous light irradiation to injured peripheral nerve: Comparative study with five different wavelengths. Laser Med Sci 4, 259–263 (1989). https://doi.org/10.1007/BF02032456
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DOI: https://doi.org/10.1007/BF02032456