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Observations on psychoneurophysiologically significant mushrooms

I. Clinical details pertaining to the ingestion of panaeolus venenosus and psilocybe caerulescens mushrooms

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Summary

The extracts ofP. venenosus, P. sphrinctrinus, Psil. mexicana, Psil. cubensis, andPsil. caerulescens have been compared by paper chromatography. It was found that neither Panaeoli contain psilocybin, the main constituent of the threePsilocybe species. The extract fromP. venenosus has been chromatographed, and two of the three major constituents were purified and obtained crystalline. One of these compounds could be shown to possess the same chromophore as psilocybin, a 4-oxygenated indole system, and seems most likely to be the active compound of the mushroom.

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Bibliography

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Authors
  1. Sam I. Stein M. D., Ph. D.
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  2. Gerhard L. Closs
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  3. Norman W. Gabel
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Additional information

Coordinator of Research and Clinical Investigator, The Bertram and Roberta Stein Neuropsychiatric Research Program, Inc.

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Stein, S.I., Closs, G.L. & Gabel, N.W. Observations on psychoneurophysiologically significant mushrooms. Mycopathologia et Mycologia Applicata 11, 205–216 (1959). https://doi.org/10.1007/BF02063078

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  • DOI: https://doi.org/10.1007/BF02063078

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