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The utilization of glucose in the brain slices during uraemia

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Abstract

Rat brain cortex slices were incubated in diluted sera obtained from patients with renal failure and from healthy persons. It was found that uraemic sera inhibited glucose uptake and the incorporation of14C-D-glucose into aspartate, glutamate and gamma-aminobutyrate (GABA). The concentration of these amino acids in the brain slices did not change.

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Authors and Affiliations

  1. 3rd Medical Clinic, Comenius University Medical School and Research Laboratory of Experimental Therapy, Institute of Human Nutrition, Bratislava, Czechoslovakia

    Eva Valovičová, V. Spustová, R. Dzúrik & P. Černáček

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  1. Eva Valovičová
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  2. V. Spustová
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  3. R. Dzúrik
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  4. P. Černáček
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Valovičová, E., Spustová, V., Dzúrik, R. et al. The utilization of glucose in the brain slices during uraemia. International Urology and Nephrology 6, 239–242 (1974). https://doi.org/10.1007/BF02089271

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  • DOI: https://doi.org/10.1007/BF02089271

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