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Die DNS-synthese im rattenherzen als funktion des lebensalters. Autoradiographische untersuchungen mit3H-thymidin

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  • Anatomica. Histologica. Carcinologica
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Summary

The percentage of DNA-synthesising heart muscle nuclei of white rats (3H-thymidine, autoradiography) decreases rapidly during the first month of life reaching a minimum at the fourth month. From then up to 27 months the number of labelled muscle nuclei remains rather constant. Also in nuclei of connective tissue the3H-thymidine labelling index decreases as a function of the rats age. The number of mitotic figures is always about 10 times lower than labelled nuclei. Mostly in heart muscle cells they occur as collapsed mitoses never leading to cytoplasma division14.

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Literatur

  1. G. Wegner undE. Mölbert, Virchows Arch. path. Anat. Physiol.341, 54 (1966).

    Article  CAS  Google Scholar 

  2. O. Klinge, Z. Zellforsch. mikrosk. Anat.80, 488 (1967).

    Article  CAS  Google Scholar 

  3. R. A. MacDonald andG. K. Mallory, Lab. Invest.8, 1547 (1959).

    CAS  Google Scholar 

  4. B. Messier andC. P. Leblond, Am. J. Anat.106, 247 (1960).

    Article  CAS  Google Scholar 

  5. H. R. Overy andR. E. Priest, Lab. Invest.15, 1100 (1966).

    CAS  Google Scholar 

  6. S. R. Pelc, Expl Cell Res.29, 194 (1963).

    Article  CAS  Google Scholar 

  7. S. R. Pelc, J. Cell Biol.22, 21 (1964).

    Article  CAS  Google Scholar 

  8. R. O. Peterson andR. Baserga, Expl Cell. Res.40, 340 (1965).

    Article  Google Scholar 

  9. P. P. Rumyantsev, Folia histochem. cytochem.1, 463 (1963).

    Google Scholar 

  10. P. P. Rumyantsev, Archs Anat. Histol. Embryol.47, 59 (1964). zit. nach: Ber. Biol.257, 14 (1966).

    CAS  Google Scholar 

  11. R. G. Shorter andJ. L. Titus, Proc. Staff Meet. Mayo Clin.37, 669 (1962).

    CAS  Google Scholar 

  12. K. Wegener, S. Hollweg undW. Maurer, Z. Zellforsch. mikrosk. Anat.63, 309 (1964).

    Article  CAS  Google Scholar 

  13. E. Stöcker, E. Teubner undG. Rosenbusch, Verh. dt. Ges. Path.48, 295 (1964).

    Google Scholar 

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Klinge, O., Stöcker, E. Die DNS-synthese im rattenherzen als funktion des lebensalters. Autoradiographische untersuchungen mit3H-thymidin. Experientia 24, 167–168 (1968). https://doi.org/10.1007/BF02146965

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  • DOI: https://doi.org/10.1007/BF02146965

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