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Bradykinin, kallidin, and their synthetic analogues

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Zusammenfassung

Biochemie und Pharmakologie der drei natürlich vorkommenden und in der Struktur bekannten Kinine — Bradykinin, Kallidin und Methionyl-Lysyl-Bradykinin — sowie deren Synthesen werden besprochen. Für die bisher bekannten 70 Analoga des Bradykinins und Kallidins wurden die biologischen Eigenschaften (Rattenuterus, Meerschweinchenileum, Kaninchenblutdruck, Meerschweinchenblutdruck, Rattenblutdruck, Bronchokonstriktoraktivität) tabellarisch zusammengestellt. Die einzelnen Analoga werden untereinander verglichen und Beziehungen zwischen Struktur und Wirksamkeit diskutiert.

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  1. Biochemische bzw. Pharmakologische Abteilung, Hauptlaboratorium der Schering AG, Berlin, Germany

    E. Schröder & R. Hempel

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Schröder, E., Hempel, R. Bradykinin, kallidin, and their synthetic analogues. Experientia 20, 529–544 (1964). https://doi.org/10.1007/BF02150278

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