Skip to main content
SpringerLink
Log in

Über einige heterozyklische Thiosemicarbazone

  • Kurze Mitteilungen
  • Published:
Experientia Aims and scope Submit manuscript

Summary

Description of 30 thiosemicarbazones of heterocyclic Aldehydes. Some of these compounds show tuberculostatic activityin vivo superior to p-Acetylaminobenzal-dehyde-thiosemicarbazone which statement was already made independently by French and American research groups. In the series of heterocyclic thiosemicarbazones very small changes in the molecular structure may cause a total loss of the tuberculostatic properties.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. G. Domagk, R. Behnisch, F. Mietzsch undH. Schmidt, Naturwissenschaften33, 315 (1946).

    Article  CAS  Google Scholar 

  2. G. Domagk, R. Behnisch, F. Mietzsch undH. Schmidt, Angew. Chemie60, 113 (1948).

    Article  Google Scholar 

  3. Geschützter Handelsname.

  4. Die Ergebnisse sind in Patentanmeldungen niedergelegt.

  5. C. Levaditi, A. Girard, A. Vaisman undA. Ray, Presse méd.58, 1326 (1950); C. r. Acad. Sci.231, 1174 (1950); Presse méd.59, 213 (1951); C. r. Acad. Sci. Soc. biol.145, 60, 861, 864 (1951); C. r. Acad. Sci.232, 770 (1951); Presse méd.59, 1606 (1951).

    Google Scholar 

  6. E. Grunberg undB. Leiwant, Proc. Soc. Exp. Biol. Med.77, 47 (1951).

    Article  CAS  Google Scholar 

  7. Th. S. Gardner, F. A. Smith, E. Wenis undJ. Lee, J. org. Chem.16, 1121 (1951).

    Article  CAS  Google Scholar 

  8. C. Levaditi, A. Girard, A. Vaisman undA. Ray, Presse méd.58, 1326 (1950); C. r. Acad. Sci.231, 1174 (1950); Presse méd.59, 213 (1951); C. r. Acad. Sci. Soc. biol.145, 60, 861, 864 (1951); C. r. Acad. Sci.232, 770 (1951); Presse méd.59, 1606 (1951).

    Google Scholar 

  9. E. Grunberg undB. Leiwant, Proc. Soc. exp. Biol. Med.77, 47 (1951).

    Article  CAS  Google Scholar 

  10. Th. S. Gardener, F. A. Smith, E. Wenis undJ. Lee, J. org. Chem.16, 1121 (1951).

    Article  Google Scholar 

  11. G. Domagk, R. Behnisch, F. Mietzsch undH. Schmidt, Angew. Chemie60, 113 (1948).

    Article  Google Scholar 

  12. Zum BeispielE. Hoggarth, A. R. Martin, N. E. Storey undE. H. P. Young, Brit. J. Pharmacol.4, 248 (1949).

    CAS  Google Scholar 

  13. R. Hirt undH. Hurni, Schweiz. Z. Path. Bakt.13, 469 (1950).

    CAS  Google Scholar 

  14. R. Donovick undJ. Bernstein et al., J. Bact.59, 667 und 675 (1950).

    Article  CAS  Google Scholar 

  15. Zum BeispielE. Hoggarth, A. R. Martin, N. E. Storey undE. H. P. Young, Brit. J. Pharmacol.4, 248 (1949).

    CAS  Google Scholar 

  16. R. Hirt undH. Hurni, Schweiz. Z. Path. Bakt.13, 469 (1950).

    CAS  Google Scholar 

  17. R. Donovick undJ. Bernstein et al., J. Bact.59, 667, 675 (1950).

    Article  CAS  Google Scholar 

  18. C. Levaditi et al., C. r. Acad. Sci.231, 1174 (1950); Smp. 227–230°.

    CAS  Google Scholar 

  19. Th. S. Gardner et al., J. org. Chem.16, 1121 (1951); Smp. 222–223°.

    Article  CAS  Google Scholar 

  20. E. Grunberg undB. Leiwant, Proc. Soc. exp. Med.77, 47 (1951), keine Smp.-Angabe.

    Article  CAS  Google Scholar 

  21. E. Grunberg et al., l. c.: keine Smp.-Angabe.

  22. J. Bernstein et al., Amer. Soc.73, 906 (1951); Smp. 149–150°.

    Article  CAS  Google Scholar 

  23. Fl. E. Anderson et al., Amer. Soc.73, 4967 (1951); Smp. 152–154°.

    Article  CAS  Google Scholar 

  24. O. Dann et al., Ber. dtsch. Chem. Ges.82, 76 (1949); Smp. 229°.

    Article  CAS  Google Scholar 

  25. P. P. T. Sah et al., Rec. trav. chim. Pays-Bas69, 1545 (1950); Smp. 236–237°.

    Article  CAS  Google Scholar 

  26. US. 2416239; allmähliche Zersetzung.

  27. EP. 620888; keine Smp.-Angabe.

  28. J. Bernstein et al., l. c.; Smp. 186–187°.

  29. Fl. E. Anderson et al., l. c.; Smp. 185–186°.

  30. Th. S. Gardner et al., l. c.; Smp. 226–227°.

  31. Fl. E. Anderson et al., l. c.; Smp. 195–197°.

Download references

Author information

Authors and Affiliations

  1. Wissenschaftliche Laboratorien der J. R. Geigy AG., Basel

    R. E. Hagenbach & H. Gysin

Authors
  1. R. E. Hagenbach
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. H. Gysin
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Hagenbach, R.E., Gysin, H. Über einige heterozyklische Thiosemicarbazone. Experientia 8, 184–185 (1952). https://doi.org/10.1007/BF02173735

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02173735

Search

Navigation