Abstract
The chemical transformations of 6-[(1-methyl-4-nitro-5-imidazolyl)thio]purine (azathiopurine) —hydrogenation, acetylation, alkylation by lower alkyl halides at positions 7 and 9 of the purine ring, hydrolytic cleavage at the C(6)−S and S−C(5) bonds— were studied.
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Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 3, pp. 372–379, March, 2000.
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Kochergin, P.M., Aleksandrova, E.V. & Korsunskii, V.S. Chemical transformations of 6-[(1-methyl-4-nitro-5-imidazolyl)-thio]purine (azathioprine). Chem Heterocycl Compd 36, 311–318 (2000). https://doi.org/10.1007/BF02256869
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DOI: https://doi.org/10.1007/BF02256869