Skip to main content
SpringerLink
Log in

Sources of error in chromatographic analysis. Effect of sampling parameters on the accuracy of numerical measurements

  • Originals
  • Published:
Chromatographia Aims and scope Submit manuscript

Summary

It is not possible in practice to carry out measurements in quantitative or qualitative analysis at a precision level better than 0.5% if conventional equipment such as recorders and electronic integrators are used to obtain the data. Only numerical techniques of on-line or off-line measurements associated with data handling by computer can be used. From their very nature numerical techniques are discontinuous and the number of experimental points is limited. According to information theory this discontinuous character does not imply a loss of accuracy provided that some simple relationship derived from the theory of sampled systems is fulfilled. These conditions deal with the choice of the sampling frequency, the frequency band-width of the amplifier and measurement system, and the upper limit of the signal frequency. We have made a theoretical and an experimental study of these phenomena and the results allow us to derive some simple rules which make the choice of parameters of the system of data acquisition easy. We have also determined the main sources of error in data acquisition systems and calculated their contribution.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

Literature

  1. Guiochon, G., Goedert, M., Jacob, L., Gas Chromatography 1970, R. Stock, ed., The Institute of Petroleum, London, 1971, p. 160.

    Google Scholar 

  2. Goedert, M., Guiochon, G., J. Chromatog. Sci.,7, 323 (1969).

    Google Scholar 

  3. Goedert, M., Guiochon, G., Anal. Chem.,42, 966 (1970).

    Google Scholar 

  4. Goedert, M., Guiochon, G., Chimie Analytique,53, 214 (1971).

    Google Scholar 

  5. Oberholtzer, J. E., Rogers, L. B., Anal. Chem.41, 1234 (1969).

    Google Scholar 

  6. Culp, R. A., Lochmuller, C. H., Moreland, A. K. Swingle, R. S., Rogers, L. B., J. Chromatog. Sci.9, 6 (1971).

    Google Scholar 

  7. Ragazzini, J. R., Franklin, G. F., Les Systèmes asservis échantillonnés, Dunod, Paris, (1962).

    Google Scholar 

  8. Stern, J., de Barberac, J., Poggi, R., Méthodes pratiques d'étude des fonctions aléatoires, Dunod, Paris (1967), p. 219.

    Google Scholar 

  9. McWilliam, G., Bolton, H. C. Anal. Chem.,41, 1755 (1969).

    Article  Google Scholar 

  10. Bassière, M., Gaignebet, E., Métrologie Générale, Dunod, Paris (1966), p. 160.

    Google Scholar 

  11. Schmauch, L. J., Anal. Chem.,31, 225 (1959).

    Google Scholar 

  12. Grushka, E., Anal. Chem.44, 1733 (1972).

    Article  Google Scholar 

  13. Sternberg, J. C., Advance in Chromatography. J. C. Giddings, R. A. Keller ed., M. Dekker, New-York, 1966, Vol. 2, p. 255.

    Google Scholar 

  14. Goedert, M., Guiochon, G., To be published. J. Chromatog. Sci.

Download references

Author information

Authors and Affiliations

  1. Laboratoire de Chimie Analytique Physique Ecole Polytechnique, rue Descartes, 17, Paris 5o, France

    M. Goedert & G. Guiochon

Authors
  1. M. Goedert
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. Guiochon
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Goedert, M., Guiochon, G. Sources of error in chromatographic analysis. Effect of sampling parameters on the accuracy of numerical measurements. Chromatographia 6, 76–83 (1973). https://doi.org/10.1007/BF02270542

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02270542

Keywords

Search

Navigation