Abstract
A system has been developed for measuring non-shunt cardiac output by the throughflow technique, using nitrous oxide in patients undergoing general anaesthesia. The throughflow measurement technique is a non-invasive method based on inert gas throughflow theory. In vitro validation of the measurement system was performed using a lung gas exchange simulator. The accuracy and precision of the throughflow measurement system was assessed by comparing measured and target values for five simulated values of non-shunt cardiac output, from 2.88 to 9.86 l min−1. This showed an overall mean bias of −0.03l min−1 (range −0.00 to −0.10 l min−1), with a mean coefficient of variation of the difference of 1.39% (1.20–1.93%). These results indicate that the measurement system is suitable for monitoring the non-shunt cardiac output in patients undergoing general anaesthesia using nitrous oxide throughflow.
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Vartuli, G.M., Burfoot, R.B., Robinson, G.J.B. et al. Development andin vitro validation of a device for measuring non-shunt cardiac output by nitrous oxide throughflow. Med. Biol. Eng. Comput. 40, 415–422 (2002). https://doi.org/10.1007/BF02345074
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DOI: https://doi.org/10.1007/BF02345074