Abstract
Peripheral vascular resistance, stroke volume, cardiac output and maximum acceleration were computed in ‘real-time’ using aortic pressure and flow signals processed by simple analogue circuits incorporated into a multichannel recording system. The use of the system was exemplified by records of the haemodynamic effects of methoxamine and adrenaline in anaesthetized dogs and noradrenaline, isoprenaline and ephedrine in unanaesthetized dogs. These analogue techniques are applicable to circulatory studies in man.
Sommaire
La résistance périphérique vasculaire, le volume de course, la sortie cardiaque et l'accélération maximum ont été calculés en ‘temps véritable’ en utilisant la pression aortique et les signaux d'écoulement préparés par des circuits analogiques simples incorporés dans un système d'enregistrement multi-canal. L'emploi du système a été exemplifié par les détails des effets haémodynamiques de la méthoxamine et de l'adrénaline chez des chiens anesthétisés et de la noradrénaline de l'isoprénaline et de l'éphédrine chez des chiens non anesthétisés. Ces techniques analogiques sont applicables aux études de la circulation chez l'homme.
Zusammenfassung
Es wurden peripherischer Gefässwiderstand, Schlagvolumen, Herzminuten-volumen und maximum Beschleunigung in ‘Real-Zeit’ unter Verwendung von Aortadruck und Flussignalen berechnet, welche durch einfache Analogschaltungen verarbeitet werden, die in ein Vielfach-Kanalschreibsystem eingebaut sind. Es wurden Beispiele für die Anwendung des Systems durch Registrierung der hämodynamischen Wirkungen von Methoxyamin und Adrenalin in betäubten Hunden und von Noradrenalin, Isoprenalin und Ephedrin in nicht betäubten Hunden gegeben. Diese Analogverfahren sind für Kreislaufuntersuchungen im Menschen anwendbar.
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References
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Hughes, R. Continuous measurement of peripheral vascular resistance and circulatory function. Med. & biol. Engng. 9, 603–610 (1971). https://doi.org/10.1007/BF02474640
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DOI: https://doi.org/10.1007/BF02474640