Skip to main content
Log in

Unit activity from peripheral nerve bundles utilizing correlation techniques

  • Published:
Medical and biological engineering Aims and scope Submit manuscript

Abstract

Recording the extracellular neuroelectric activity at several sites along a nerve trunk provides information on single unit action potential shape and conduction velocity. Several correlation techniques are examined for separating the multi-unit neuroelectric activity into the activity of single nerve fibres. An instrument is described that simultaneously separates multi-unit recordings, made at two sites along a nerve trunk, into single unit activity.

Sommaire

L'enregistrement de l'activité neuroélectrique extracellulaire à différents points au long d'une artère nerveuse fournit des renseignements sur la forme de potentiel d'action d'une simple unité et sur la vélocité de conduction. Plusieurs techniques de corrélation sont examinées pour séparer l'activité neuroélectrique multi-unitaire en activité de fibres nerveuses simples. On décrit un instrument qui sépare simultanément des enregistrements multi-unitaires pris à deux endroits au long d'une artère nerveuse simple.

Zusammenfassung

Registrierung extrazellularer neuroelektrischer Aktivität an verschiedenen Stellen entlang einem Nervenstrang ergibt Information über Potentialform der Handlung und über Leifähigkeitsgeschwindigkeit einer einzigen Einheit. Es werden mehrere Korrelations-techniken zur Trennung der neuroelektrischen Aktivität der Multi-Einheit in die Aktivitäten einzelner Nervenfasern untersucht. Es wird ein Apparat beschrieben, der gleichzeitig Multi-Einheit Aufschreibungen, die an zwei Stellen entlang einem Nervenstrang gemacht werden, in Aktivität einer einzelnen Einheit trennt.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  • Bessou, P. andPearl, E. R. (1969) Response to cutaneous sensory units with unmyelinated fibers to noxious stimuli.J. Neurophysiol. 32, 1025–1043.

    Google Scholar 

  • Bomze, H. A. andEisenstein, B. A. (1968) Decomposition method of analyzing nerve potentials.Proc. 21st ACEMB Conf. 4, 1.

    Google Scholar 

  • Bradley, W., Conway, C., Glover, E. andMcCormick, S. (1967) Discriminator and integrator instrument for an on-line frequency analysis of single unit discharges.Electroenceph. clin. Neurophysiol. 22 177–179.

    Article  Google Scholar 

  • Casby, J. V., Siminoff, R. andHouseknecht, T. R. (1963) An analogue cross-correlator to study naturally induced activity in intact nerve trunks.J. Neurophysiol.26, 432–448.

    Google Scholar 

  • Dill, J. C., Lockemann, P. C. andNaka, K. I. (1970) An attempt to analyze multi-unit recordings.Electroenceph. clin. Neurophysiol.28 79–82.

    Article  Google Scholar 

  • Erlanger, J., Gasser, H. S. andBishop, G. H. (1924) The compound nature of the action current of nerve as disclosed by the cathode ray oscillograph.Am. J. Physiol.70, 624–666.

    Google Scholar 

  • Frank, K. (1968) Some approaches to the technical problem of chronic excitation of peripheral nerve.Ann. Otology, Rhin. Laryng. 77, 761–771.

    Google Scholar 

  • Friedman, D. H. (1968)Detection of Signals by Template Matching. Johns Hopkins Press.

  • Gerstein, G. L. andClark, W. A. (1964) Simultaneous studies of firing patterns in several neurons.Science, N. Y. 143, 1325–1327.

    Google Scholar 

  • Glaser, E. M. andMarks, W. B. (1966) The on-line separation of interleaved neuronal pulse sequences. 1966Rochester Conf. on Data Acquisition in Biol. and Med. 137–156.

  • Hambrecht, F. T. Unpublished data.

  • Herman, H. T., Stark, L. andWillis, P. A. (1962) Instrumentation for processing neural signals.Electroenceph. clin. Neurophysiol. 14 557–560.

    Article  Google Scholar 

  • Keehn, D. G. (1966) An iterative spike separation technique.IEEE Trans. bio-med. Electron. BME-13, 19–28.

    Google Scholar 

  • Littauer, R. M. andWalcott, C. (1959) Pulse-height analyzer for neurophysiological applications.Rev. scient Instrum. 30, 1102–1106.

    Article  Google Scholar 

  • MacPherson, L. andLennon, W. J. (1967) A digital technique for selecting action potential pulses of a specific height.Med biol., Engng 5, 401–404.

    Google Scholar 

  • Martin, A. R. (1969) A peak amplitude selector for electrophysiological data analysis.IEEE Trans. biomed. Electron. BME-16 152–159.

    Google Scholar 

  • McCann, G. D. andRay, C. B. (1963) Computers and data processing for nervous system research.IEEE Trans. bio-med. Electron. BME-10, 48–56.

    Article  Google Scholar 

  • McCann, G. D. andRay, C. B. (1966) An information processing and control system for biological research.Ann. N. Y. Acad. Sci. 128, 830–848.

    Google Scholar 

  • Mishelevich, D. J. (1970) On-line real-time digital computer separation of extracellular neuroelectric signals.IEEE Trans. bio-med. Electron. BME-17 147–150.

    Google Scholar 

  • Mortimer, T. (1965) The design and evaluation of an action potential discriminator.Case Inst. Tech. Report No. EDC4-65-12.

  • Plumb, G. O. (1965) Pulse height analyzer for electrophysiology.J. Physiol. 179, 16P-17P.

    Google Scholar 

  • Poggio, G. F. andMountcastle, V. B. (1963) The functional properties of ventrobasal thalamic neurons studied in unanesthetized monkeys.J. Neurophysiol.26, 775–806.

    Google Scholar 

  • Simon, W. (1965) The real-time sorting of neuro-electric action potentials in multiple unit studies.Electroenceph. clin. Neurophysiol. 18, 192–195.

    Article  Google Scholar 

  • Spalla, L. J. andBoudreau, J. C. (1967) A solid state differential amplitude discriminator for single unit recording.Electroenceph. clin. Neurophysiol. 23, 477–480.

    Article  Google Scholar 

  • Schmidt, E. M. (1968) Solid state delay of analog signals,IEEE J. solid-st. Circ. SC-3, 179–181.

    Article  Google Scholar 

  • Schmidt, E. M. andStromberg, M. W. (1969) Computer dissection of peripheral nerve bundle activity.Computers Biomed. Res. 5, 446–455.

    Article  Google Scholar 

  • Schmidt, E. M. (1971) An instrument for separation of multiple unit neuroelectric signals.IEEE Trans. biomed. Electron. in press.

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Schmidt, E.M. Unit activity from peripheral nerve bundles utilizing correlation techniques. Med. & biol. Engng. 9, 665–674 (1971). https://doi.org/10.1007/BF02474647

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02474647

Keywords

Navigation