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Quantitative determination of furocoumarins in samples of “Carapiá” by capillary gas chromatography

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Summary

The occurrence of furocoumarins in the Moraceae has already been demostrated. We present here the results concerning the chemical composition and quantification of furocoumarins from “carapiá” (Dorstenia species, Moraceae) employed in Brazil because of its medicinal properties against skin diseases. A capillary gas chromatographic procedure is described for the simultaneous determination of the furocoumarins (psoralen, bergapten, pimpinellin, and isopimpinellin) in rhizomes and aerial parts ofDorstenia tubicina, Dorstenia asaroides andDorstenia vitifolia and in commercial samples. The method is shown to be sensitive and reproducible, and may have application in the analysis of “carapia” crude drugs.

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References

  1. L. C. Di Stasi, C. A. Hiruma, E. M. Guimařaes, C. M. Santos, Fitoterapia,6, 529 (1994).

    Google Scholar 

  2. W. Vilegas, J. H. Y. Vilegas, G. L. Pozetti, Rev. Cienc. Farm.,14, 133 (1994).

    Google Scholar 

  3. J. H. Y. Vilegas, F. M. Lanças, W. Vilegas, G. L. Pozetti, Phytochemical Analysis,4, 230 (1993).

    CAS  Google Scholar 

  4. W. Vilegas, J. H. Y. Vilegas, G. L. Pozetti, Rev. Latinoamer. Quim.,23(2), 78 (1994).

    CAS  Google Scholar 

  5. J. H. Y. Vilegas, W. Vilegas, C. de F. Camilot, G. L. Pozetti, Rev. Cienc. Farm.,12, 89 (1990).

    CAS  Google Scholar 

  6. R. M. Kuster, R. R. Bernardo, A. J. R. da Silva, J. P. Parente, W. B. Mors, Phytochemistry36, 221 (1994).

    Article  CAS  Google Scholar 

  7. F. C. Hoehne, “Plantas e substâncias vegetais tóxicas e medicinais”, Departamento de Botânica do estado de Šao Paulo, Šao Paulo (1939), p. 45.

    Google Scholar 

  8. Seplantec “Inventário de plantas medicinais do estado de Bahia”, Secretária de Ciência e Tecnologia, Salvador (1979), p. 410.

    Google Scholar 

  9. M. A. Pathak, T. B. Fitzpatrick, J. Photochem. Photobiol.14B, 3 (1992).

    Google Scholar 

  10. A. Bettero, C. A. Benassi, Farmaco36, 140 (1981).

    CAS  Google Scholar 

  11. F. Mahuzier, O. Carreau, M. Pascal, C. Machali, P. Lebret, S. Locq, P. Forlot, in T. B. Fitzpatrick, P. Forlot, M. A. Pathak, F. Urbach, (Ed.) Psoralens, Past, Present and Future of Photochemoprotection and other Biological Activies, John Libbey Eurotext, Paris, 1989, p. 263.

    Google Scholar 

  12. B. R. Scott, M. A. Pathak, G. R. Mohn, Mutat. Res.39, 29 (1976).

    CAS  Google Scholar 

  13. L. Musajo, G. Rodighiero, Experientia18, 153 (1962).

    Article  CAS  Google Scholar 

  14. D. A. Grekin, J. H. Epstein, Photochem. Photobiol.33, 957 (1981).

    CAS  Google Scholar 

  15. R. Roelandts, Arch. Dermatol.120, 662 (1984).

    Article  CAS  Google Scholar 

  16. W. H. Koch, Mutat. Res.160, 195 (1986).

    CAS  Google Scholar 

  17. G. W. Ivie, J. Agric. Food Chem.26, 1394 (1978).

    Article  CAS  Google Scholar 

  18. A. Bettero, C. A. Benassi, J. Chromtogr.280, 167 (1983).

    Article  CAS  Google Scholar 

  19. H. N. Nigg, J. O. Strandberg, R. C. Beier, H. D. Petersen, J. M. Harrison, J. Agric. Food Chem.45, 1430 (1997).

    Article  CAS  Google Scholar 

  20. G. Innocenti, A. Piovan, R. Caniato, R. Filippini, E. M. Cappelletti, Int. J. of Pharmacog.34 (2), 114 (1996).

    Article  CAS  Google Scholar 

  21. D. Chouchi, D. Barth, J. Chromatogr.672, 177 (1994).

    Article  CAS  Google Scholar 

  22. J. H. Y. Vilegas, F. M. Lanças, W. Vilegas, G. L. Pozetti, J. Braz. Chem. Soc.8 (5), 529 (1997).

    Article  CAS  Google Scholar 

  23. G. Innocenti, A. Piovan, R. Filippini, R. Caniato, E. M. Cappelletti, Phytochem. Anal.8, 84 (1997).

    Article  CAS  Google Scholar 

  24. F. Bourgaud, N. Allard, P. Forlot, A. Guckert, Agronomy10, 1 (1990).

    Google Scholar 

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Authors and Affiliations

  1. Departamento de Química Analítica, Instituto de Química de Araraquara, Universidade Estadual Paulista, Caixa Postal 355, 14800-900, Araraquara, SP, Brasil

    C. A. L. Cardoso

  2. Departamento de Química Orgânica, Instituto de Química de Araraquara, Universidade Estadual Paulista, Caixa Postal 355, 14800-900, Araraquara, SP, Brasil

    W. Vilegas

  3. Departamento de Química, Universidade Federal de Mato Grosso do Sul, Caixa Postal 649, 79070-900, Campo Grande, MS, Brasil

    N. K. Honda

Authors
  1. C. A. L. Cardoso
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  2. W. Vilegas
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  3. N. K. Honda
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Cardoso, C.A.L., Vilegas, W. & Honda, N.K. Quantitative determination of furocoumarins in samples of “Carapiá” by capillary gas chromatography. Chromatographia 50, 11–14 (1999). https://doi.org/10.1007/BF02493610

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  • DOI: https://doi.org/10.1007/BF02493610

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