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Isolation of an inhibitor responsible for abnormal glucose utilization in liver disease

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Summary

An inhibitor of glucose utilization in rat diaphragm was isolated from the serum of patients suffering from liver cirrhosis. This inhibitor is suggested to contribute to abnormal carbohydrate metabolism in liver diseases. It is a low molecular weight substance, probably of pepticle nature. It is identical with the inhibitor of glucose utilization isolated from the serum and urine of patients with renal failure and from the urine of healthy subjects.

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References

  1. Creutzfeldt W., Frerichs H., Sickinger K.: Liver Diseases and Diabetes Mellitus — In:Popper H., Schaffner F. (Eds): Progress in Liver Disease. Grune and Stratton, New York, 1969; vol. 3, p. 371.

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  2. Dzúrik R., Hupková V., Černáček P., Valovičová E., Niederland T. R.: The Isolation of an Inhibitor of Glucose Utilization from the Serum of Uraemic Subjects — Clin. chim. Acta46, 77, 1973.

    Article  PubMed  Google Scholar 

  3. Dzúriková V., Niederland T. R., Brixová E., Dzúrik R., Hupková V., Holomáň J.: Abnormal Carbohydrate Metabolism in Patients with Liver Cirrhosis; in Vitro Study — Diabetologia8, 202, 1972.

    Article  PubMed  Google Scholar 

  4. Felber J.-P., Magnenat P., Vannotti A.: Tolérance au glucose diminuée et réponse insulinique élevée dans la cirrhose — Schweiz. med. Wschr.97, 1537, 1967.

    PubMed  CAS  Google Scholar 

  5. Megyesi C., Samols E., Marks V.: Glucose Tolerance and Diabetes in Chronic Liver Disease — Lancet2, 1051, 1967.

    Article  PubMed  CAS  Google Scholar 

  6. Spustová-Hupková V., Černáček P., Dzúrik R.: The Isolation of the Inhibitor of Glucose Utilization from Urine of Uraemic and Healthy Subjects — Physiol. bohemoslov. (In press).

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Authors and Affiliations

  1. Research Laboratory of Experimental Therapy, Institute of Human Nutrition, and III. Medical Clinic, Comenius University Medical School, Bratislava

    Viera Dzúriková, Peter Černáěk, Teofil R. Niederland & Rastislav Dzúrik

Authors
  1. Viera Dzúriková
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  2. Peter Černáěk
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  3. Teofil R. Niederland
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  4. Rastislav Dzúrik
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Dzúriková, V., Černáěk, P., Niederland, T.R. et al. Isolation of an inhibitor responsible for abnormal glucose utilization in liver disease. Acta diabet. lat 11, 277–282 (1974). https://doi.org/10.1007/BF02581232

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  • DOI: https://doi.org/10.1007/BF02581232

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