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Myogenic tone and cerebral vascular autoregulation: The role of a stretch-dependent mechanism

  • Autoregulation of Cerebral Blood Flow
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Conclusion

Cerebral vessels of many mammalian species exhibit stretch-dependent or myogenic tone which would be expected to contribute to autoregulation. This tone is dependent on extracellular calcium and probably involves mechanisms other than those associated with agonist and potassium-induced tone. This tone may be contingent upon the redistribution of strategic substances within the cell membrane.

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Authors and Affiliations

  1. Department of Pharmacology, University of Vermont College of Medicine, Given Medical Building, 05405, Burlington, Vermont

    John A. Bevan & Joyce J. Hwa

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  1. John A. Bevan
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  2. Joyce J. Hwa
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Research supported by USPHS Grant No. HL 32985.

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Bevan, J.A., Hwa, J.J. Myogenic tone and cerebral vascular autoregulation: The role of a stretch-dependent mechanism. Ann Biomed Eng 13, 281–286 (1985). https://doi.org/10.1007/BF02584245

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  • DOI: https://doi.org/10.1007/BF02584245

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