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Towards a genetic architecture of cryptic genetic variation and genetic assimilation: The contribution of K. G. Bateman

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References

  • Bateman K. G. 1959 The genetic assimilation of four venation phenocopies.J. Genet. 56, 443–474.

    Article  Google Scholar 

  • Bier E. 2000 Drawing lines in theDrosophila wing: initiation of wing vein development.Curr. Opin. Genet. Dev. 10, 393–398.

    Article  PubMed  CAS  Google Scholar 

  • Conley C. A., Silburn R., Singer M. A., Ralston A., Rohwer-Nutter D. and Olson, D.J. et al. 2000 Crossveinless 2 contains cysteine-rich domains and is required for high levels of BMP-like activity during the formation of the cross veins inDrosophila.Development 127, 3947–3959.

    PubMed  CAS  Google Scholar 

  • Denholm B., Brown S., Ray R. P., Ruiz-Gomez M., Skaer H. and Hombria J. C. 2005Crossveinless-c is a RhoGAP required for actin reorganisation during morphogenesis.Development 132, 2389–2400.

    Article  PubMed  CAS  Google Scholar 

  • Dworkin I., Palsson A., Birdsall K. and Gibson G. 2003 Evidence thatEgfr contributes to cryptic genetic variation for photoreceptor determination in natural populations ofDrosophila melanogaster.Curr. Biol. 13, 1888–1893.

    Article  PubMed  CAS  Google Scholar 

  • Dworkin I., Palsson A. and Gibson G. 2005 Replication of anEgfr-wing shape association in a wild-caught cohort ofDrosophila melanogaster.Genetics 169, 2115–2125.

    Article  PubMed  CAS  Google Scholar 

  • Falconer D. and Mackay T. F. C. 1996Introduction to quantitative genetics, 4th Edn. Longman, New York.

    Google Scholar 

  • Feder M., Blair N. and Figueras H. 1997 Natural thermal stress and heat-shock protein expression inDrosophila larvae and pupae.Func. Ecol. 11, 90–100.

    Article  Google Scholar 

  • Gibson G. and Dworkin I. 2004 Uncovering cryptic genetic variation.Nature Rev. Genet. 5, 681–690.

    Article  CAS  PubMed  Google Scholar 

  • Gibson G. and Hogness D. S. 1996 Effect of polymorphism in theDrosophila regulatory gene ultrabithorax on homeotic stability.Science 271, 200–203.

    Article  PubMed  CAS  Google Scholar 

  • Gibson G., Wemple M. and van Helden S. 1999 Potential variance affecting homeotic ultrabithorax and antennapedia phenotypes inDrosophila melanogaster.Genetics 151, 1081–1091.

    PubMed  CAS  Google Scholar 

  • Marcus J. M. 2001 The development and evolution of crossveins in insect wings.J. Anat. 199, 211–216.

    Article  PubMed  CAS  Google Scholar 

  • Milkman R. D. 1960 The genetic basis of natural variation.I. Crossveins inDrosophila melanogaster.Genetics 45, 35–48.

    PubMed  CAS  Google Scholar 

  • Milkman R. D. 1961 The genetic basis of natural variation. III. Developmental lability and evolutionary potential.Genetics 46, 25–38.

    PubMed  CAS  Google Scholar 

  • Milkman R. D. 1962 The genetic basis of natural variation. IV. On the natural distribution ofcve polygenes ofDrosophila melanogaster.Genetics 47, 261–272.

    PubMed  CAS  Google Scholar 

  • Mohler J. D. 1965a Influence of some crossveinless-like genes on crossveinless phenocopy sensitivity inDrosophila melanogaster.Genetics 51, 329–340.

    PubMed  CAS  Google Scholar 

  • Mohler J. D. 1965b Preliminary genetic analysis of crossveinless-like strains ofDrosophila melanogaster.Genetics 51, 641–651.

    PubMed  CAS  Google Scholar 

  • Pritchard J. K. 2001 Are rare variants responsible for susceptibility to complex diseases?Am. J. Hum. Genet. 69, 124–137.

    Article  PubMed  CAS  Google Scholar 

  • Pritchard J. K. and Cox N. J. 2002 The allelic architecture of human disease genes: common disease-common variant…or not?Hum. Mol. Genet. 11, 2417–2423.

    Article  PubMed  CAS  Google Scholar 

  • Ralston A. and Blair S. S. 2005 Long-range Dpp signaling is regulated to restrict BMP signaling to a crossvein competent zone.Dev. Biol. 280, 187–200.

    Article  PubMed  CAS  Google Scholar 

  • Serpe M., Ralston A., Blair S. S. and O’Connor M. B. 2005 Matching catalytic activity to developmental function: tolloid-related processes Sog in order to help specify the posterior crossvein in theDrosophila wing.Development 132, 2645–2656.

    Article  PubMed  CAS  Google Scholar 

  • Shimmi O., Ralston A., Blair S. S. and O’Connor M. B. 2005 The crossveinless gene encodes a new member of the Twisted gastrulation family of BMP-binding proteins which, with Short gastrulation, promotes BMP signaling in the crossveins of the Drosophila wing.Dev. Biol. 282, 70–83.

    Article  PubMed  CAS  Google Scholar 

  • Vilmos P., Sousa-Neves R., Lukacsovich T. and Marsh J. L. 2005 Crossveinless defines a new family of Twisted-gastrulation-like modulators of bone morphogenetic protein signalling.EMBO Rep. 6, 262–267.

    Article  PubMed  CAS  Google Scholar 

  • Waddington C. H. 1942 The canalization of development and the inheritance of acquired characters.Nature 150, 563.

    Google Scholar 

  • Waddington C. H. 1948 The genetic control of development.Symp. Soc. Exper. Biol. 2, 145–154.

    Google Scholar 

  • Waddington C. H. 1952 Selection of the genetic basis for an acquired character.Nature 169, 625–626.

    Article  PubMed  CAS  Google Scholar 

  • Waddington C. H. 1953 Genetic assimilation of an acquired character.Evolution 7, 118–126.

    Article  Google Scholar 

  • Waddington C. H. 1956 Genetic assimilation of the bithorax phenotype.Evolution 10, 1–13.

    Article  Google Scholar 

  • Williams K. D., Helin A. B., Posluszny J., Roberts S. P. and Feder, M. E. 2003 Effect of heat shock, pretreatment and hsp70 copy number on wing development inDrosophila melanogaster.Mol. Ecol. 12, 1165–1177.

    Article  PubMed  CAS  Google Scholar 

  • Yu K., Srinivasan S., Shimmi O., Biehs B., Rashka K. E. and Kimelman D.et al. 2000 Processing of theDrosophila Sog protein creates a novel BMP inhibitory activity.Development 127, 2143–2154.

    PubMed  CAS  Google Scholar 

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Correspondence to Ian Dworkin.

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Dworkin, I. Towards a genetic architecture of cryptic genetic variation and genetic assimilation: The contribution of K. G. Bateman. J Genet 84, 223–226 (2005). https://doi.org/10.1007/BF02715794

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