Abstract
The effect of lipid lowering agents of plant origin garlic oil and guggulipid on the levels of catecholamine and dopamine Β-hydroxylase activity of normal and cholesterol fed rabbit tissues has been studied. The catecholamine levels and enzyme activity were found to be decreased in cholesterol (500 mg/kg body wt) fed animals. The feeding of garlic oil (5 mg/kg body wt) and guggulipid (100 mg/kg body wt) an exudate ofCommiphora mukul, to normal rabbits caused significant increase in the dopamine-Β-hydroxylase activity and catecholamine levels, while the feed helped the hypercholesterolemic rabbits to recover the decrease in catecholamine biosynthesis
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Abbreviations
- DBH:
-
Dopamine Β-hydroxylase
- E:
-
epinephrine
- NE:
-
norepinephrine
- DA:
-
dopamine
- 5-HT:
-
serotonin
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C.D.R.I. Communication No. 3435.
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Srivastava, M., Nityanand, S. & Kapoor, N.K. Effect of hypocholesterolemic agents of plant origin on catecholamine biosynthesis in normal and cholesterol fed rabbits. J Biosci 6, 277–282 (1984). https://doi.org/10.1007/BF02716741
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DOI: https://doi.org/10.1007/BF02716741