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Changes in hepatic ribonucleoproteins in Kwashiorkor

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Summary and Conclusion

Using the toluidine blue-ammonium molybdate staining method, different types of RNPs were demonstrated in the hepatocytes of patients with kwashiorkor. DCR-I and DCR-III were found to be reduced. Nucleolar chromatin and nucleolar parachromatin showed an apparent increase. Chromosomal, perichromosomal and nuclear parachromatin remained unaffected. Granular cytoplasmic RNP was nonreactive in all the cases.

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References

  • Agarwal, V.P. and Bharadwaj, T.P. (1972). The probable morphogenetic evolution of Indian childhood cirrhosis.Indian Pediat. 9, 323.

    CAS  Google Scholar 

  • Agarwal, V.P., Sachdev, K.N. and Chaudhury, V.K. (1972). Indian childhood cirrhosis—a cytochemical study of hepatic hyaline.Ibid. p. 294.

    CAS  Google Scholar 

  • Gopalan, C. and Ramalingaswami, V. (1955). Kwashiorkor in India.Ind. J. Med. Res. 43, 751.

    CAS  Google Scholar 

  • Love, R. and Bharadwaj, T.P. (1959). Two types of RNPs in the nucleolus of mammalian cells.Nature,183, 1453.

    Article  PubMed  CAS  Google Scholar 

  • Love, R. and Liles, R.H. (1959). Differentiation of nucleoproteins by inactivation of protein-bound amino groups and staining with toluidine blue and ammonium molybdate.J. Histochem. 7, 164.

    CAS  Google Scholar 

  • Love, R. and Walsh, R. (1963). Cytochemistry of nucleoproteins. II. Improved staining methods with toluidine blue and ammonium molybdate.J Histochem. Cytochem. 11, 188.

    CAS  Google Scholar 

  • Ramalingaswami, V., Sriramachari, S. and Patwardhan, V.N. (1954). Liver injury in protein malnutrition.Ind. J. Med. Sci. 8, 433.

    Google Scholar 

  • Ramanathan, M.K. (1955). Biochemical changes in serum in nutritional oedema syndrome (Kwashiorkor).Ind. J. Med. Ros. 43, 517.

    CAS  Google Scholar 

  • Thompson, S.W. (1966). Selected histochemical and hiostpathological methods. Charles C. Thomas, Springfield.

    Google Scholar 

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From the Department of Pathology, S P. Medical College, Bikaner.

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Agarwal, V.P., Bharadwaj, T.P. Changes in hepatic ribonucleoproteins in Kwashiorkor. Indian J Pediatr 40, 8–11 (1973). https://doi.org/10.1007/BF02755285

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