Summary
Diazo-positive cells in mouse duodenal mucosa proliferate only in the same zone as epithelial cells (bottom and lower parts of the crypts). Their rate of proliferation as well as their speed of migration into the villi are slower than those of epithelial cells, but to a minor extent only. It is suggested that a special cytokinetic behaviour appears earlier than morphological argentaffin differentiation.
Zusammenfassung
Diazo-positive Zellen der Duodenalschleimhaut proliferieren wie gewöhnliche Epithelien in den unteren Kryptenabschnitten. Ihre Proliferationsrate und ihre Wandergeschwindigkeit in die Zottenspitze sind aber etwas langsamer als diejenige gewöhnlicher Epithelien. Man muß annehmen, daß die besonderen cytokinetischen Eigenschaften Diazo-positiver Zellen bereits vor der morphologisch nachweisbaren argentaffinen Ausdifferenzierung vorhanden sind.
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Supported by the Swiss National Foundation for Scientific Research.
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Odartchenko, N., Hedinger, C., Ruzicka, J. et al. Cytokinetics of argentaffin cells in mouse intestinal mucosa. Virchows Arch. Abt. B Zellpath. 6, 132–136 (1970). https://doi.org/10.1007/BF02899118
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DOI: https://doi.org/10.1007/BF02899118