Skip to main content
SpringerLink
Log in

Gallic and tannic acids inhibit the mutagenicity of a direct acting mutagen N-methyl-N’-nitro-N-nitrosoguanidine, but not of a Promutagen Dimethylnitrosamine inArabidopsis thaliana

  • Brief Communication
  • Published:
Biologia Plantarum

Abstract

Gallic and tannic acids reduced the frequency of mutations induced by a direct acting mutagen N-methyl-N’-nitro-N-nitrosoguanidine (MNNG) but had no effect on the mutagenicity of a promutagen dimethylnitrosamine inArabidopsis thaliana. Polarographic studies demonstrated a chemical interaction between MNNG and both phenolic acids.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  • Gichner, T., Pospíšl, F., Velemínský, J., Volkeová, V., Volke, J.: Two types of the antimutagenic effects of gallic and tannic acids towards N-nitroso compounds-induced mutagenicity in the AmesSalmonella assay. - Folia microbiol. (submitted to press), 1986.

  • Müller, A. J.: Embryonentest zum Nachweiss rezessiver Letalfaktoren beiArabidopsis thaliana. - Biol. Zentralbl.82: 113–163, 1963.

    Google Scholar 

  • Müller, A. J.: Mutationsauslösung durch Nitrosomethylharnstoff beiArabidopsis. - Züchter34: 102–120, 1964.

    Article  Google Scholar 

  • Pospíšil, F.: Polarography of 3,4,5-trihvdroxybenzoic acid. - Coll. czechosl. chem. Commun.49: 1459–1463, 1984.

    Google Scholar 

  • Shimoi, K., Nakamura, Y., Tomita, I., Kada, T.: Bio-antimutagenic effects of tannic acid on UV and chemically induced mutagenesis inEscherichia coli B/r. - Mutation Res.149: 17–23, 1985.

    PubMed  CAS  Google Scholar 

  • Stich, H. F., Rosin, M. P.: Naturally occurring phenolics as antimutagenic and anticarcinogenic agents. - In:Friedman, M. (ed.): Toxicological Aspects of Food Safety. Pp. 1–29. Plenum Press, New York-London 1984.

    Google Scholar 

  • Wood, A. W., Huang, M. T., Chang, R. L., Newmark, H. L., Yagi, R. E., Sayer, J. M., Jerina, D. M., Conney, A. H.: Inhibition of the mutagenicity of bay-region diol epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: Exceptional activity of ellagic acid. - Proc. nat. Acad. Sci. USA79: 5513–5517, 1982.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Institute of Experimental Botany, Czechoslovak Academy of Sciences, Flemingovo n. 2, 160 00 Praha 6, Praha, Czechoslovakia

    T. Gichner, F. Pospíšl & J. Velemínský

  2. I. Heyrovský Institute of Physical Chemistry and Electrochemistry, Czechoslovak Academy of Sciences, Vlašská 9, 118 00 Praha 1, Praha, Czechoslovakia

    Věra Volkeová & J. Volke

Authors
  1. T. Gichner
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. F. Pospíšl
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Věra Volkeová
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. J. Volke
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. J. Velemínský
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Gichner, T., Pospíšl, F., Volkeová, V. et al. Gallic and tannic acids inhibit the mutagenicity of a direct acting mutagen N-methyl-N’-nitro-N-nitrosoguanidine, but not of a Promutagen Dimethylnitrosamine inArabidopsis thaliana . Biol Plant 28, 386–390 (1986). https://doi.org/10.1007/BF02902252

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02902252

Keywords

Search

Navigation