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The heat-stable exotoxin ofBacillus thuringiensis

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References

  • Angus T. A.: A bacterial toxin paralysing silkworm larvae.Nature173, 545 (1954).

    Article  PubMed  CAS  Google Scholar 

  • Angus T. A.: Extraction, purification and properties ofBacillus sotto toxin.Canad. J. Microbiol.2, 416 (1956).

    CAS  Google Scholar 

  • Angus T. A., Norris J. R.: A comparison of the toxicity of some varieties ofBacillus thuringiensis Berliner for silkworm larvae.J. Invertebrate Path.11, 289 (1968).

    Article  Google Scholar 

  • Barjac H. de,Bonnefoi A.: A classification of strains ofBacillus thuringiensis Berliner with a key to their differentiation.J. Invertebrate Pathol.11, 335 (1968).

    Article  Google Scholar 

  • Barjac H. de,Burgerjon A.: Studies on the presence of the thermostable toxin in serotypes 10, 11 and 12 ofBacillus thuringiensis.J. Invertebrate Pathol.21, 325 (1973).

    Article  Google Scholar 

  • Barjac H. de,Burgerjon A., Bonnefoi A.: The production of heat-stable toxin by nine serotypes ofBacillus thuringiensis.J. Invertebrate Pathol.8, 537 (1966).

    Article  Google Scholar 

  • Barjac H. de,Dedonder R.: Isolement d'un nucléotide identifiable a la “toxine thermostable” deBacillus thuringiensis var. Berliner.Compt. Rend. Acad. Sci., Paris260, 7050 (1965).

    Google Scholar 

  • Barjac H. de,Dedonder R.: Purification de la toxine thermostable deBacillus thuringiensis et analyses complémentaires.Bull Soc. Chim. Biol.50, 941 (1968).

    PubMed  Google Scholar 

  • Barjac H. de,Dumanoir V. C.: Comparison entre les exotoxines thermostables de differents sérotypes deBacillus thuringiensis.Compt. Rend. Acad. Sci., Paris278, 2843 (1974).

    Google Scholar 

  • Barjac H. de,Riou J. Y.: Action de la toxine thermostable deBacillus thuringiensis var.thuringiensis administrée a des souris.Revue Path. Comp. Méd. Exp.6, 368 (1969).

    Google Scholar 

  • Barjac H. de,Lecadet, M. M.: Dosage biochemique de l'exotoxine thermostable deBacillus thuringiensis d'apres l'inhibition d'ARN-polymerases bactériennes.Compt. Rend. Acad. Sci., Paris,282, 2119 (1976).

    Google Scholar 

  • Beebee T. J., Bond R. P. M.: Different ribonucleic acid polymerase activities in larval and adult blowflies.Proc. Biochem. Soc. 91P (1973a).

  • Beebee T. J., Bond R. P. M.: Effect of the exotoxin ofBacillus thuringiensis on normal and ecdysone-stimulated ribonucleic acid polymerase activity in intact nuclei from the fat body ofSarcophaga bullata larvae.Biochem. J.136, 1 (1973b).

    PubMed  CAS  Google Scholar 

  • Beebee T. J. C., Bond R. P. M.: Effect of an exotoxin fromBacillus thuringiensis on deoxyribonucleic acid-dependent ribonucleic polymerase in nuclei from adultSarcophaga bullata.Biochem. J.136, 9 (1973c).

    PubMed  CAS  Google Scholar 

  • Beebee T. J. C., Korner A., Bond R. P. M.: Differential inhibition of mammalian ribonucleic acid polymerases by an exotoxin fromBacillus thuringiensis. The direct observation of nucleoplasmic ribonucleic acid polymerase activity in intact nuclei.Biochem. J.127, 619 (1972).

    PubMed  CAS  Google Scholar 

  • Benz G.: On the chemical nature of the heat-stable exotoxin ofBacillus thuringiensis.Experientia22, 81 (1966).

    Article  PubMed  CAS  Google Scholar 

  • Benz G., Perron J. M.: The toxic action ofBacillus thuringiensis “exotoxin” onDrosophila reared in yeast-containing and yeast-free media.Experientia23, 871 (1967).

    Article  PubMed  CAS  Google Scholar 

  • Bond R. P. M.: The natural occurence of allomucic (allaric) acid: A contribution to the asignment of structure of an insecticidal exotoxin fromBacillus thuringiensis Berliner.Chem. Commun. 338 (1969).

  • Bond R. P. M., Boyce C. B. C., French S. J.: A purification and some properties of an insecticidal exotoxin fromBacillus thuringiensis Berliner.Biochem. J.114, 477 (1969).

    PubMed  CAS  Google Scholar 

  • Bonnefoi A.: Procédé d'obtention de produits biologiques pour la lutte contre les insectes nuisibles à l'agriculture. French Patent 1, 225, 179 (1960).

  • Briggs J. D.: Reduction of adult house-fly emergence by the effects ofBacillus spp. on the development of immature forms.J. Insect Pathol.2, 418 (1960).

    Google Scholar 

  • Broesma D. B., Buxton J. A.: A comparative study of the action of six crystalliferous bacteria on the cabbage looperTrichoplusia ni.J. Invertebrate Pathol.9, 58 (1967).

    Article  Google Scholar 

  • Burgerjon A.: Effects physiologiques et mutagenes sur les insectes de la toxine thermostable deBacillus thuringiensis Berliner.Ann. Parasitol. Humaine Comp.48, 835 (1974).

    Google Scholar 

  • Burgerjon A., Barjac H. de: Nouvelles données sur le role de la toxine soluble thermostable produite parBacillus thuringiensis Berliner.Compt. Rend. Acad. Sci., Paris251, 911 (1960).

    CAS  Google Scholar 

  • Burgerjon A., Barjac H. de: Étude de la toxine soluble thermostable chez differentes souches deBacillus thuringiensis. Compt. Rend. Congr. Intern. Pathol. Insects, Paris, 835 (1962).

  • Burgerjon A., Barjac H. de: Étude de la toxine soluble thermostable chez differentes souches de-Bacillus thuringiensis Berliner.Mém. Hors Sér. Entomophaga No. 2, 221 (1964).

    Google Scholar 

  • Burgerjon A., Barjac H. de: Another serotype (4: 4a, 4c) ofBacillus thuringiensis which produces thermostable toxin.J. Invertebrate Pathol.9, 574 (1967).

    Article  Google Scholar 

  • Burgerjon A., Biache G.: The activity of the heat-stable toxin ofBacillus thuringiensis Berliner used in nature against the larvae ofDiprion pini (Linnaeus).J. Insect Pathol.6, 538 (1964).

    Google Scholar 

  • Burgerjon A., Biache G.: Contribution to the studies of the activity spectra of the strains ofBacillus thuringiensis Berliner. Insect Pathology and microbial Control, Proceed. International Coll. Wageningen 1966, 294 (1967a).

  • Burgerjon A., Biache G.: Contribution a l'étude du spectre d'activité de différentés souches deBacillus thuringiensis.Ent. Exp. Appl.10, 211 (1967b).

    Article  Google Scholar 

  • Burgerjon A., Biache G., Cals Ph.: Teratology of the Colorado potate beetle,Leptinotarsa decemlineata, as provoked by larval administration of the thermostable toxin ofBacillus thuringiensis.J. Invertebrate Pathol.14, 274 (1969).

    Article  Google Scholar 

  • Burgerjon A., Grison P., Kachkouli A.: Activity of the heat-stable toxin ofBacillus thuringiensis B. inLocusta migratoria (Linnacus) (Locustidae, Orthoptera).J. Insect Pathol.6, 381 (1964).

    Google Scholar 

  • Burges H. D.: Teratogenicity of the thermostable β-exotoxin ofBacillus thuringiensis inGalleria mellonella.J. Invertebrate Pathol.26, 419 (1975).

    Article  Google Scholar 

  • Cantwell G. E., Heimpel A. M., Thompson M. J.: The production of an exotoxin by various crystal-forming bacteria related toBacillus thuringiensis var.thuringiensis Berliner.J. Insect Pathol.6, 466 (1964).

    Google Scholar 

  • Carlberg G.: Biological effects of the thermostable β-exotoxin produced by different serotypes ofBacillus thuringiensis.Reports Dept. Microbiol. Univ. Helsinki6, 90 (1973).

    Google Scholar 

  • Drake B. B., Smythe C. V.: U.S. Pat, 3,087,865 (1961).

  • Farkaš J., Šebesta K., Horská K., Samek Z., Dolejš L., Šorm F.: The structure of exotoxin ofBacillus thuringiensis var.gelechiae.Coll. Czech. Chem. Commun.34, 1118 (1969).

    Google Scholar 

  • Hannay C. L.: Crystaline inclusions in aerobic sporeforming bacteria.Nature172, 1004 (1953).

    Article  PubMed  CAS  Google Scholar 

  • Heimpel A. M.: A strain ofBacillus cereus Fr. and Fr. pathogenic for the larch sawflyPristiphora erichsonii (Htg.).Can. Entomologist86, 73 (1954).

    Article  Google Scholar 

  • Heimpel A. M.: Investigation of the mode of action of strain ofBacillus cereus Fr. and Fr. pathogenic for the larch sawfly,Pristiphora erichsonii (Htg.).Can. J. Zool.33, 311 (1955).

    Article  Google Scholar 

  • Heimpel A. M.: A critical review ofBacillus thuringiensis var.thuringiensis Berliner and other crystalliferous bacteria.Ann. Rev. Entomol.12, 287 (1967).

    Article  CAS  Google Scholar 

  • Horská K., Kalvoda L., Šebesta K.: Inhibition of DNA-dependent RNA polymerase by derivatives and analogues of thuringiensin.Coll. Czech. Chem. Commun.41, 3837 (1976).

    Google Scholar 

  • Horská K., Vaňková J., Šebesta K.: Determination of exotoxin inBacillus thuringiensis cells.Z. Naturforsch.30c, 120 (1975).

    Google Scholar 

  • Iandolo J. J., Powell R. L., Bulla Jr.L. A.: Dormant spores ofBacillus thuringiensis contain an inhibitor of RNA polymerase.Biochem. Biophys. Res. Commun.,69, 237 (1976).

    Article  PubMed  CAS  Google Scholar 

  • Ignoffo C. M., Gregory B.: Effects ofBacillus thuringiensis β-exotoxin on larvae maturation, adult longevity, fecundity and egg viability in several species ofLepidoptera.Envir. Ent.1, 269 (1972).

    CAS  Google Scholar 

  • Kalvoda L., Prystaš M., Šorm F.: Nucleic acid component and their analogues. CLX. Determination of the structure of the allaric portion by means of periodate oxidation.Coll. Czech. Chem. Commun.38, 2529 (1973).

    CAS  Google Scholar 

  • Kalvoda L., Prystaš M., Šorm F.: Synthesis of exotoxin byBacillus thuringiensis. I. Formation of the ethereal bond between ribose and glucose.Coll. Czech. Chem. Commun.41, 788 (1976a).

    CAS  Google Scholar 

  • Kalvoda L., Prystaš M., Šorm F.: Synthesis of exotoxin produced byBacillus thuringiensis. II. Formation of the α-glucosidic bond, nucleosidation, phosphorylation.Coll. Czech. Chem. Commun.41, 800 (1976b).

    CAS  Google Scholar 

  • Kim Y. T., Gregory B. G., Ignoffo C. M.: The β-exotoxins ofBacillus thuringiensis. III. Effects onin vivo synthesis of macromolecules in an insect system.J. Invertebrate Pathol.20, 46 (1972a).

    Article  CAS  Google Scholar 

  • Kim Y. T., Gregory B. G., Ignoffo C. M., Shapiro M.: The β-exotoxin ofBacillus thuringiensis. IV. Effects onin vitro synthesis of macromolecules in an insect cell line.J. Invertebrate Pathol.20, 284 (1972b).

    Article  CAS  Google Scholar 

  • Kim Y. T., Huang H. T.: The β-exotoxins ofBacillus thuringiensis. I. Isolation and characterization.J. Invertebrate Pathol.15, 100 (1970).

    Article  CAS  Google Scholar 

  • Krieg A.: Über den Biotest vonBacillus thuringiensis β-exotoxin mitDrosophila melanogaster.Ent. Exp. Appl.9, 185 (1966).

    Google Scholar 

  • Krieg A.: Neues überBacillus thuringiensis und seine Anwendung.Mitt. Biol. Bundesanst. Berlin-Dahlem Heft125, 106 (1967).

    Google Scholar 

  • Krieg A.: Über die Differenzierung der Mäuse-Toxicität desBacillus cereus und desBacillus thuringiensis von der Mäuse-Pathogenität desBacillus anthracis.Zbl. Bakt., I. Abt. Orig.215, 523 (1970).

    CAS  Google Scholar 

  • Krieg A.: Concerning β-exotoxin produced by vegetative cells ofBacillus thuringiensis andBacillus cereus.J. Invertebrate Pathol.17, 134 (1971).

    Article  CAS  Google Scholar 

  • Krieg A., Herfs W.: Empfindlichkeit verschiedener Insektenarten gegenüber dem “Exotoxin” vonBacillus thuringiensis Berliner.Z. Pfl. Krankh. Pflschutz.70, 11 (1963).

    CAS  Google Scholar 

  • Kushner D. J., Heimpel A. M.: Lecithinase production by strains ofBacillus cereus Fr. et Fr. pathogenic for the larch sawfly,Pristiphora erichsonii (Htg.)Can. J. Microbiol.3, 547 (1957).

    PubMed  CAS  Google Scholar 

  • Lam A. B. D., Webster J. M.: Effect of the DD-136 Nematode and of a β-exotoxin preparation ofBacillus thuringiensis var.thuringiensis on leatherjackets,Tipula paludosa larvae.J. Invertebrate Pathol.20, 141 (1972).

    Article  CAS  Google Scholar 

  • Lüthy P.: Zur bakteriologischen Schädlinsbekämpfung: Die entomopathogenen Bacillus-Arten,Bacillus thuringiensis undBacillus popilliae.Vierteljahrsschrift Naturforsch. Ges. Zürich120, 81 (1975).

    Google Scholar 

  • Mackedonski V. V.: Effect of the exotoxin ofBacillus thuringiensis on the biosynthesis and maturation of mouse liver nuclear RNA.Biochim. Biophys. Acta390, 319 (1975).

    PubMed  CAS  Google Scholar 

  • Mackedonski V. V., Hadjiolov A. A.: Inhibition of DNA dependent RNA polymerase of isolated mice liver nuclei by the exotoxin ofBacillus thuringiensis.Comp. Rend. Acad. Sci. Bulgare27, 1117 (1974).

    Google Scholar 

  • McConnell E., Richards A. G.: The production byBacillus thuringiensis Berliner of a heat-stable substance toxic for insects.Canad. J. Microbiol.6, 161 (1959).

    Article  Google Scholar 

  • Megna J. C.: U. S. Pat. 3,073,749 (1963).

  • Norris J. R.: Sporeformers as insecticides.J. Appl. Bact.33, 192 (1970).

    CAS  Google Scholar 

  • Prystaš M., Kalvoda L., Šorm F.: Alternative synthesis of exotoxin fromBacillus thuringiensis.Coll. Czech. Chem. Commun.41, 1426 (1976).

    Google Scholar 

  • Rogoff M. H.: Crystal forming bacteria as insect pathogens.Adv. Appl. Microbiol.8, 291 (1966).

    CAS  Google Scholar 

  • Rosenberg G., Carlberg G., Gyllenberg H. G.: Microbiological assay of the β-exotoxin ofBacillus thuringiensis.J. Appl. Bact.34, 417 (1971).

    CAS  Google Scholar 

  • Schmid E., Benz G.: Oral and parenteral toxicity ofBacillus thuringiensis “exotoxin” and its inactivation in larvae ofGalleria mellonella.Experientia25, 96 (1969).

    Article  PubMed  CAS  Google Scholar 

  • Šebesta K., Horská K.: Inhibition of DNA-dependent RNA polymerase by the exotoxin ofBacillus thuringiensis var.gelechiae.Biochim. Biophys. Acta169, 281 (1968).

    PubMed  Google Scholar 

  • Šebesta K., Horská K.: Mechanism of inhibition of DNA-dependent RNA polymerase by exotoxin ofBacillus thuringiensis.Biochim. Biophys. Acta209, 357 (1970).

    PubMed  Google Scholar 

  • Šebesta K., Horská K.: The fate of exotoxin fromBacillus thuringiensis in mice.Coll. Czech. Chem. Commun.38, 2533 (1973).

    Google Scholar 

  • Šebesta K., Horská K., Vaňková J.: Isolation, purification and toxicity of a thermostable exotoxin from the strain ofBacillus gelechiae Auct. In “Insect Pathology and Microbial Control” (P. A. van der Laan, ed.) p. 238, Amsterdam 1967.

  • Šebesta K., Horská K., Vaňková J.: Isolation and properties of the insecticidal exotoxin ofBacillus thuringiensis var.gelechiae Auct.Coll. Czech. Chem. Commun.34, 891 (1969a).

    Google Scholar 

  • Šebesta K., Horská K., Vaňková J.: Inhibition of de novo RNA synthesis by the insecticidal exotoxin ofBacillus thuringiensis var.gelechiae.Coll. Czech. Chem. Commun.34, 1786 (1969b).

    Google Scholar 

  • Šebesta K., Horská K., Vaňková J.: Estimation of exotoxin production by different strains ofBacillus thuringiensis using32P—labelled exotoxin.Coll. Czech. Chem. Commun.38, 298 (1973).

    Google Scholar 

  • Šebesta K., Sternbach H.: The specifity of inhibition of DNA-dependent RNA polymerase byBacillus thuringiensis exotoxin.FEBS Letters8, 233 (1970).

    Article  PubMed  Google Scholar 

  • Smirnoff W. A.: Consideration on the toxic and labile substance produced byBacillus thuringiensis Berliner (labile exotoxin).Entomophaga, Mém. Hors. Sér.2, 244 (1964).

    Google Scholar 

  • Smirnoff W. A., Berlinguet L.: A substance in some commercial preparations ofBacillus thuringiensis var.thuringiensis toxic to sawfly larvae.J. Invertebrate Pathol.8, 376 (1966).

    Article  CAS  Google Scholar 

  • Smuckler E. A., Hadjiolov A. A.: Inhibition of hepatic deoxyribonucleic acid-dependent ribonucleic acid polymerases by the exotoxin ofBacillus thuringiensis in comparison with the effects of α-amanitin and cordycepin.Biochem. J.129, 153 (1972).

    PubMed  CAS  Google Scholar 

  • Sommerville H. J.: Microbial toxins.Ann. N. Y. Acad. Sci.217, 93 (1973).

    Article  Google Scholar 

  • Steinhaus E. A.: Possible use ofBacillus thuringiensis Berliner as an aid in the biological control of the alfaalfa caterpillar.Hilgardia20, 359 (1951).

    Google Scholar 

  • Toumanoff C.: Description de quelques souches entomophytes deBacillus cereus F. et F. avec remarques sur leur action et celle d'autres bacilles sur le jaune d'oeuf.Ann. Inst. Pasteur85, 90 (1953).

    CAS  Google Scholar 

  • Vaňková J.: Study on the effect ofBacillus thuringiensis on insects.Folia biologica3, 175 (1957).

    Google Scholar 

  • Vaňková J.: Kultivierung vonBacillus thuringiensis im Versuchsbetriebsmasstab.Trans. I. Int. Conf. Insect Pathology and Biol. Control, Prague, p. 59 (1958).

  • Vaňková J.:Bacillus thuringiensis in praktischer Anwendung.Coll. Int. Pathol. Insectes, Paris1962, 281 (1964).

  • Vaňková J.: Pathogenicity of different strains of theBacillus thuringiensis group forGalleria mellonella.Acta bohemoslov.63, 10 (1966).

    Google Scholar 

  • Vaňková J., Horská K.: The activity of gut phosphatase in some insect species and the effects of gut homogenates on the exotoxin ofBacillus thuringiensis in vitro.Acta Entomol. Bohemoslov.72, 7 (1975).

    Google Scholar 

  • Vaňková J., Horská K., Šebesta K.: The fate of exotoxin ofBacillus thuringiensis inGalleria mellonella caterpillars.J. Invertebrate Pathol.23, 209 (1974).

    Article  Google Scholar 

  • Vaňková J., Leskova Ja.: Changes in the haemolymph ofGalleria mellonella (L.) caterpillars infected by the exotoxin ofBacillus thuringiensis.Acta Entomol. Bohemoslov.69, 297 (1972).

    Google Scholar 

  • Wasti S. S., Mahadeo C. R., Knell J. D.: Larvicidal activity of the β-exotoxin ofBacillus thuringiensis var.thuringiensis Berliner against two species of flies.Z. Angew. Entomol.74, 157 (1973).

    Google Scholar 

  • Weiser J.: The survey of our recent results in the research of Insect diseases. (In Czech).Acta Soc. Entomol. Čechoslov.52, 61 (1955).

    Google Scholar 

  • Wolfenbarger D. A., Guerra A. A., Dulmage H. T., Garcia R. D.: Properties of the β-exotoxin ofBacillus thuringiensis IMC 10,000 against the tobacco budworm.J. Econ. Entomol.65, 1245 (1972).

    PubMed  CAS  Google Scholar 

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Vaňková, J. The heat-stable exotoxin ofBacillus thuringiensis . Folia Microbiol 23, 162–174 (1978). https://doi.org/10.1007/BF02915317

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