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Non-reciprocal crossing over in phage λ

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Abstract

In replication-blocked crosses in phage λ,cos, λ’s packaging origin, provokes Red-mediated recombination in its neighborhood. In crosses of wild-type x mutantcos, cosstimulated crossover products can be packaged fromcos sites cloned medially in the two parents (Stahl F W, Kobayashi I and Stahl M M 1985J. Mol. Biol. 181: 199–209). We find that the complementary crossover products are not produced in equal numbers. In agreement with the model presented earlier (ibid), most of the recombinants inherit λ’ s right arm (R arm) from thecos +parent and λ’s left arm (A arm) from the parent with the mutantcos.

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Stahl, F.W., Stahl, M.M. Non-reciprocal crossing over in phage λ. J. Genet. 64, 31–39 (1985). https://doi.org/10.1007/BF02923551

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  • DOI: https://doi.org/10.1007/BF02923551

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