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Antioxidative components from the aerial Parts ofLactuca scariola L

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  • Medicinal Chemistry & Natural Products
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Abstract

The antioxidant activity ofLactuca scariola (Compositae) was investigated by measuring the radical scavenging effect on DPPH (1,1-diphenyl-2-picrylhydrazyl) radical. The methanolic extract of the aerial parts ofLactuca scariola showed strong radical scavenging activity. The EtOAc soluble fraction exhibited a stronger activity than the others, and was purified by silica gel and Sephadex LH-20 column chromatography. Quercetin-3-O-P-D-glucopyranoside, luteolin-7-O-β-D-glucopyranoside, luteolin, quercetin and kaempferol, together with 11β,13-dihydrolactucin were isolated from the EtOAc soluble fraction as active ingredients.

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  1. College of Pharmacy, Woosuk University, 565-701, Samrye, Korea

    Dae-Keun Kim

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Correspondence to Dae-Keun Kim.

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Kim, DK. Antioxidative components from the aerial Parts ofLactuca scariola L. Arch Pharm Res 24, 427–430 (2001). https://doi.org/10.1007/BF02975189

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  • DOI: https://doi.org/10.1007/BF02975189

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