Abstract
Three new dammarane glycosides were isolated from the processed ginseng (SG; Sun Ginseng). Their structure were determined to be 3β,12β-dihydroxydammar-20(21),24-diene-3-O-β-D-glucopyranosyl(1 → 2)-β-D-glucopyranoside; 3β,12β-dihydroxydammar-20(21),24-diene-3-O-β-D- glucopyranoside and 3β,6α,12β-trihydroxydammar-20(21),24-diene-6-O-β-D-glucopyr-anoside based on spectroscopic evidences. The compounds were named as ginsenoside Rk1 Rk2, and Rk3 respectively.
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Baek, N. I., Kim, D. S., Lee, Y. H., Park, J. D., Lee, C. B., and Kim, S. I., Ginsenoside Rh4, A Genuine Dammarane Glycoside from Korean Red Ginseng.Planta Med., 62, 86–87 (1996).
Han, D.S.,Pharmacognogy, Dong Myoung Sa, Seoul, 1988
Keum, Y. S., Park, K. K., Lee, J. M., Chun, K. S., Park, J. H., Lee, S. K., Kwon, H. J., and Surh, Y. J., Antioxidant and antitumor promoting activities of the methanol extract of heat-processed ginseng.Cancer Letters, 150, 41–48 (2000).
Kim, D. S., Baek, N. I., Park, J. D., Lee, Y. H., Jeong, S. Y., Lee, C. B., and Kim, S. I., Preparation and Structure Determination of a New Glycoside, (20E)-Ginsenoside Rh3, and its isomer from Diol-type Ginseng Saponins.Yakhak Hoeji, 39, 85–93 (1995).
Kim, S. I., Baek, N. I., Kim, D. S., Lee, Y. H., Kang, K. S., and Park J. D., Preparation of a 20(S)-Ginsenoside Rh2 and the 20(S) Epimer from Protopanaxadiol Saponins ofPanax ginseng C.A. Meyer.Yakhak Hoeji, 35, 432–437 (1991).
Kim, S. I., Kim, D. S., Lee, Y. H., Park, J. D., and Baek, N. I., Isolation of A Novel Dammarane-Glycoside, Ginsenoside Rh4, from Korean Red Ginseng.Proceedings of 95 Korean-Japan Ginseng Symposium, 107 (1995).
Kim, S. I., Park, J. D., Lee, Y. H., Nam, G. Y., and Baek, N. I., Preparation of 20(R)- and 20(S)-Ginsenoside Rh1 from Ginsenoside Re.Korean J. Ginseng Sci., 15, 188–191 (1991).
Kim, S. I., Park, J. H., Ryu, J. H., Park, J. D., Lee, Y. H., Park, J. H., Kim, T. H., Kim, J. M., and Baek, N. I., Ginsenoside Rg5, A Genuine Dammarane Glycoside from Korean Red Ginseng.Arch. Pharm. Res., 19(5), 551–553 (1996).
Kim, W. Y., Kim, J. M., Han, S. B., Lee, S. K., Kim, N. D., Park, M. K., Kim, C. K., Park, J. H., Steaming of Ginseng at High Temperature Enhances Biological Activity.J. Nat. Prod., 63, 1702–1704 (2000).
Kitagawa, I., Yoshikawa, M., Yoshigara, M., Hayashi, T. and Taniyama, T., Chemical Studies on Crude Drug Precession. I. On the Constitution of Ginseng Radix Rubra (1).Yakugaku Zasshi, 103, 612–622 (1983).
Ryu, J. H., Park, J. H., Eun, J. H., Jung, J. H., and Sohn, D. H., A dammarane glycoside from Korean red ginseng.Phytochemistry, 44, 931–933 (1997).
Sanada, S., Kondo, N., Shoji, J., Tanaka, O., and Shibata, S., Studies on the saponins of Ginseng. I. Structure of Ginsenoside-Ro, -Rb1, -Rb2, -Rc and Rd.Chem. Pharm. Bull., 22(2), 421–428 (1974a).
Sanada, S., Kondo, N., Shoji, J., Tanaka, O., and Shibata, S., Studies on the saponins of Ginseng. II. Structure of Ginsenoside-Re, -Rf, and Rg2.Chem. Pharm. Bull., 22(10), 2407–2412 (1974b).
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Park, I.H., Kim, N.Y., Han, S.B. et al. Three new dammarane glycosides from heat processed ginseng. Arch Pharm Res 25, 428–432 (2002). https://doi.org/10.1007/BF02976595
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DOI: https://doi.org/10.1007/BF02976595