Skip to main content

Advertisement

SpringerLink
Log in

Hintergrundpapier der STIKO: Evaluation der bestehenden Influenzaimpfempfehlung für Indikationsgruppen und für Senioren (Standardimpfung ab 60 Jahren)

  • Tätigkeitsbericht
  • Published:
Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz Aims and scope

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Literatur

  1. Wu Y, Wu Y, Tefsen B, Shi Y, Gao GF (2014) Bat-derived influenza-like viruses H17N10 and H18N11. Trends Microbiol 22(4):183–191

    Article  CAS  PubMed  Google Scholar 

  2. Biere B, Bauer B, Schweiger B (2010) Differentiation of influenza B virus lineages Yamagata and Victoria by real-time PCR. J Clin Microbiol 48(4):1425–1427

    Article  PubMed  PubMed Central  Google Scholar 

  3. WHO (1980) A revision of the system of nomenclature for influenza viruses: a WHO memorandum. Bull World Health Organ. 1980;58(4):585–91.

  4. Nobusawa E, Sato K (2006) Comparison of the mutation rates of human influenza A and B viruses. J Virol 80(7):3675–3678

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Kreijtz JH, Fouchier RA, Rimmelzwaan GF (2011) Immune responses to influenza virus infection. Virus Res 162(1–2):19–30

    Article  CAS  PubMed  Google Scholar 

  6. Mandell GL, Bennett JE, Dolin R (2010) Mandell, Douglas, and Bennett's principles and practice of infectious diseases, 7. Aufl. Churchill Livingstone, Elsevier, Philadelphia

    Google Scholar 

  7. Leung NH, Xu C, Ip DK, Cowling BJ (2015) Review article: the fraction of influenza virus infections that are asymptomatic: a systematic review and meta-analysis. Epidemiology 26(6):862–872

    Article  PubMed  PubMed Central  Google Scholar 

  8. Hayward AC, Fragaszy EB, Bermingham A, Wang L, Copas A, Edmunds WJ et al (2014) Comparative community burden and severity of seasonal and pandemic influenza: results of the Flu Watch cohort study. Lancet Respir Med 2(6):445–454

    Article  PubMed  Google Scholar 

  9. Coates BM, Staricha KL, Wiese KM, Ridge KM (2015) Influenza A virus infection, innate immunity, and childhood. JAMA Pediatr 169(10):956–963

    Article  PubMed  PubMed Central  Google Scholar 

  10. Mertz D, Kim TH, Johnstone J, Lam PP, Science M, Kuster SP et al (2013) Populations at risk for severe or complicated influenza illness: systematic review and meta-analysis. BMJ 347:f5061

    Article  PubMed  PubMed Central  Google Scholar 

  11. Thomas RE (2014) Is influenza-like illness a useful concept and an appropriate test of influenza vaccine effectiveness? Vaccine 32(19):2143–2149

    Article  CAS  PubMed  Google Scholar 

  12. Monto AS, Gravenstein S, Elliott M, Colopy M, Schweinle J (2000) Clinical signs and symptoms predicting influenza infection. Arch Intern Med 160(21):3243–3247

    Article  CAS  PubMed  Google Scholar 

  13. World Health Organization (2014) Influenza (seasonal). Fact sheet No. 211. March 2014. http://www.who.int/mediacentre/factsheets/fs211/en/Accessed on 01.11.2016

    Google Scholar 

  14. Robert Koch Institute (2014) Bericht zur Epidemiologie der Influenza in Deutschland Saison 2014/15. RKI, Berlin

    Google Scholar 

  15. Robert Koch-Institut (2014) Die Arbeitsgemeinschaft Influenza als zentrales Instrument im Gesamtkonzept der Influenzaüberwachung in Deutschland. Epidemiol Bull 40:391–396

    Google Scholar 

  16. Grund S, Wichmann O, Mertens T, Hengel H (2013) Concepts, effectiveness, and perspectives of pandemic and seasonal influenza vaccines. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 56(1):76–86

    Article  CAS  PubMed  Google Scholar 

  17. Paul-Ehrlich-Institut (2015) Informationen zu den in Deutschland zugelassenen Impfstoffen, den freigegebenen Impfstoffdosen und der Impfstoff-Stammzusammensetzung für die Saison 2015/2016. http://www.pei.de/DE/infos/fachkreise/impfungen-impfstoffe/influenza-grippeimpfstoffe-saisonal/influenza-grippeimpfstoffe-node.html. Zugegriffen: 03. Feb 2016

    Google Scholar 

  18. Orenstein WA, Bernier RH, Hinman AR (1988) Assessing vaccine efficacy in the field. Further observations. Epidemiol Rev 10:212–241

    CAS  PubMed  Google Scholar 

  19. De Serres G, Skowronski DM, Wu XW, Ambrose CS (2013) The test-negative design: validity, accuracy and precision of vaccine efficacy estimates compared to the gold standard of randomised placebo-controlled clinical trials. Euro Surveill. doi:10.2807/1560-7917.es2013.18.37.20585

    Google Scholar 

  20. Jackson ML, Nelson JC (2013) The test-negative design for estimating influenza vaccine effectiveness. Vaccine 31(17):2165–2168

    Article  PubMed  Google Scholar 

  21. Skowronski DM, Janjua NZ, De Serres G (2013) Understanding suboptimal influenza vaccine effectiveness within the agent, host, and environment paradigm. Clin Infect Dis 57(3):476–477

    Article  PubMed  Google Scholar 

  22. Beyer WE, de Bruijn IA, Palache AM, Westendorp RG, Osterhaus AD (1999) Protection against influenza after annually repeated vaccination: a meta-analysis of serologic and field studies. Arch Intern Med 159(2):182–188

    Article  CAS  PubMed  Google Scholar 

  23. Ohmit SE, Petrie JG, Malosh RE, Cowling BJ, Thompson MG, Shay DK et al (2013) Influenza vaccine effectiveness in the community and the household. Clin Infect Dis 56(10):1363–1369

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  24. Ständige Impfkommission (STIKO) (2015) Mitteilung der Ständigen Impfkommission am Robert Koch-Institut (RKI). Empfehlungen der Ständigen Impfkommission (STIKO) am Robert Koch-Institut. Robert Koch-Institut, Berlin, Deutschland

    Google Scholar 

  25. Ständige Impfkommission (STIKO) (2014) Standardvorgehensweise (SOP) der Ständigen Impfkommission (STIKO) für die systematische Entwicklung von Impfempfehlungen. Version 2.0 vom 06.02.2014. http://www.rki.de/DE/Content/Kommissionen/STIKO/Aufgaben_Methoden/SOP.pdf?__blob=publicationFileZugegriffen: 01.11.2016

    Google Scholar 

  26. Shea BJ, Grimshaw JM, Wells GA, Boers M, Andersson N, Hamel C et al (2007) Development of AMSTAR: a measurement tool to assess the methodological quality of systematic reviews. Bmc Med Res Methodol 7:10

    Article  PubMed  PubMed Central  Google Scholar 

  27. Moher D, Liberati A, Tetzlaff J, Altman DG, Group P (2009) Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 151(4):264–269 (W64)

    Article  PubMed  Google Scholar 

  28. Higgins J, Green S (2011) Cochrane Handbook for Systematic Reviews of Interventions Version 5.1.0. :The Cochrane Collaboration, London, England

    Google Scholar 

  29. Critical Appraisal Skills Programme (CASP) (2014) CASP checklists. CASP, Oxford

    Google Scholar 

  30. Guyatt GH, Oxman AD, Schunemann HJ, Tugwell P, Knottnerus A (2011) GRADE guidelines: a new series of articles in the Journal of Clinical Epidemiology. J Clin Epidemiol 64(4):380–382

    Article  PubMed  Google Scholar 

  31. Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P et al (2008) GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ 336(7650):924–926

    Article  PubMed  PubMed Central  Google Scholar 

  32. Guyatt GH, Thorlund K, Oxman AD, Walter SD, Patrick D, Furukawa TA et al (2013) GRADE guidelines: 13. Preparing summary of findings tables and evidence profiles-continuous outcomes. J Clin Epidemiol 66(2):173–183

    Article  PubMed  Google Scholar 

  33. Van Kerkhove MD, Vandemaele KA, Shinde V, Jaramillo-Gutierrez G, Koukounari A, Donnelly CA et al (2011) Risk factors for severe outcomes following 2009 influenza A (H1N1) infection: a global pooled analysis. PLOS Med 8(7):e1001053

    Article  PubMed  PubMed Central  Google Scholar 

  34. Buda S, Kopke K, Haas W (2010) Epidemiological characteristics of the influenza pandemic (H1N1) 2009 in Germany based on the mandatory notification of cases. Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz 53(12):1223–1230

    Article  CAS  PubMed  Google Scholar 

  35. Remschmidt C, Wichmann O, Harder T (2014) Methodological quality of systematic reviews on influenza vaccination. Vaccine 32(15):1678–1684

    Article  PubMed  Google Scholar 

  36. Atashili J, Kalilani L, Adimora AA (2006) Efficacy and clinical effectiveness of influenza vaccines in HIV-infected individuals: a meta-analysis. BMC Infect Dis 6:138

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  37. Remschmidt C, Wichmann O, Harder T (2014) Influenza vaccination in HIV-infected individuals: systematic review and assessment of quality of evidence related to vaccine efficacy, effectiveness and safety. Vaccine 32(43):5585–5592

    Article  CAS  PubMed  Google Scholar 

  38. Madhi SA, Maskew M, Koen A, Kuwanda L, Besselaar TG, Naidoo D et al (2011) Trivalent inactivated influenza vaccine in African adults infected with human immunodeficient virus: double blind, randomized clinical trial of efficacy, immunogenicity, and safety. Clin Infect Dis 52(1):128–137

    Article  CAS  PubMed  Google Scholar 

  39. Tasker SA, Treanor JJ, Paxton WB, Wallace MR (1999) Efficacy of influenza vaccination in HIV-infected persons. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 131(6):430–433

    Article  CAS  PubMed  Google Scholar 

  40. Ranieri R, Veronelli A, Santambrogio C, Pontiroli AE (2005) Impact of influenza vaccine on response to vaccination with pneumococcal vaccine in HIV patients. AIDS Res Hum Retroviruses 21(5):407–409

    Article  CAS  PubMed  Google Scholar 

  41. Yamanaka H, Teruya K, Tanaka M, Kikuchi Y, Takahashi T, Kimura S et al (2005) Efficacy and immunologic responses to influenza vaccine in HIV-1-infected patients. J Acquir Immune Defic Syndr 39(2):167–173

    CAS  PubMed  Google Scholar 

  42. Fine AD, Bridges CB, De Guzman AM, Glover L, Zeller B, Wong SJ et al (2001) Influenza A among patients with human immunodeficiency virus: an outbreak of infection at a residential facility in New York City. Clin Infect Dis 32(12):1784–1791

    Article  CAS  PubMed  Google Scholar 

  43. Madhi SA, Dittmer S, Kuwanda L, Venter M, Cassim H, Lazarus E et al (2013) Efficacy and immunogenicity of influenza vaccine in HIV-infected children: a randomized, double-blind, placebo controlled trial. AIDS 27(3):369–379

    Article  CAS  PubMed  Google Scholar 

  44. Remschmidt C, Wichmann O, Harder T (2015) Vaccines for the prevention of seasonal influenza in patients with diabetes: systematic review and meta-analysis. BMC Med 13(1):53

    Article  PubMed  PubMed Central  Google Scholar 

  45. Hak E, Nordin J, Wei F, Mullooly J, Poblete S, Strikas R et al (2002) Influence of high-risk medical conditions on the effectiveness of influenza vaccination among elderly members of 3 large managed-care organizations. Clin Infect Dis 35(4):370–377

    Article  PubMed  Google Scholar 

  46. Heymann AD, Shapiro Y, Chodick G, Shalev V, Kokia E, Kramer E et al (2004) Reduced hospitalizations and death associated with influenza vaccination among patients with and without diabetes. Diabetes Care 27(11):2581–2584

    Article  PubMed  Google Scholar 

  47. Isotani H (2000) Use of influenza vaccine in patients with diabetes, particularly those with complications of cardiac or renal disease. Intern Med 39(10):862

    Article  CAS  PubMed  Google Scholar 

  48. Rodriguez-Blanco T, Vila-Corcoles A, de Diego C, Ochoa-Gondar O, Valdivieso E, Bobe F et al (2012) Relationship between annual influenza vaccination and winter mortality in diabetic people over 65 years. Hum Vaccin Immunother 8(3):363–370

    Article  PubMed  Google Scholar 

  49. Schade CP, McCombs MA (2000) Influenza immunization and mortality among diabetic medicare beneficiaries in West Virginia. W V Med J 96(3):444–448

    CAS  PubMed  Google Scholar 

  50. Selvais PL, Hermans MP, Donckier JE, Buysschaert M (1997) Reported rates, incentives, and effectiveness of major vaccinations in 501 attendees at two diabetes clinics. Diabetes Care 20(7):1212–1213

    Article  CAS  PubMed  Google Scholar 

  51. The American Lung Association Asthma Clinical Research Centers (2001) The safety of inactivated influenza vaccine in adults and children with asthma. N Engl J Med 345(21):1529–1536

    Article  Google Scholar 

  52. Colquhoun AJ, Nicholson KG, Botha JL, Raymond NT (1997) Effectiveness of influenza vaccine in reducing hospital admissions in people with diabetes. Epidemiol Infect 119(3):335–341

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  53. Gasparini R, Amicizia D, Lai PL, Rossi S, Panatto D (2013) Effectiveness of adjuvanted seasonal influenza vaccines (Inflexal V (R) and Fluad (R) ) in preventing hospitalization for influenza and pneumonia in the elderly: a matched case-control study. Hum Vaccin Immunother 9(1):144–152

    Article  CAS  PubMed  Google Scholar 

  54. Lau D, Eurich DT, Majumdar SR, Katz A, Johnson JA (2013) Effectiveness of influenza vaccination in working-age adults with diabetes: a population-based cohort study. Thorax 68(7):658–663

    Article  PubMed  PubMed Central  Google Scholar 

  55. Looijmans-Van den Akker I, Verheij TJ, Buskens E, Nichol KL, Rutten GE, Hak E (2006) Clinical effectiveness of first and repeat influenza vaccination in adult and elderly diabetic patients. Diabetes Care 29(8):1771–1776

    Article  PubMed  Google Scholar 

  56. Wang IK, Lin CL, Chang YC, Lin PC, Liang CC, Liu YL et al (2013) Effectiveness of influenza vaccination in elderly diabetic patients: a retrospective cohort study. Vaccine 31(4):718–724

    Article  CAS  PubMed  Google Scholar 

  57. Remschmidt C, Wichmann O, Harder T (2014) Influenza vaccination in patients with end-stage renal disease: systematic review and assessment of quality of evidence related to vaccine efficacy, effectiveness, and safety. BMC Med 12(1):244

    Article  PubMed  PubMed Central  Google Scholar 

  58. Bond TC, Spaulding AC, Krisher J, McClellan W (2012) Mortality of dialysis patients according to influenza and pneumococcal vaccination status. Am J Kidney Dis 60(6):959–965

    Article  PubMed  Google Scholar 

  59. Gilbertson DT, Unruh M, McBean AM, Kausz AT, Snyder JJ, Collins AJ (2003) Influenza vaccine delivery and effectiveness in end-stage renal disease. Kidney Int 63(2):738–743

    Article  PubMed  Google Scholar 

  60. McGrath LJ, Kshirsagar AV, Cole SR, Wang L, Weber DJ, Sturmer T et al (2012) Influenza vaccine effectiveness in patients on hemodialysis: an analysis of a natural experiment. Arch Intern Med 172(7):548–554

    Article  PubMed  PubMed Central  Google Scholar 

  61. Slinin Y, Foley RN, Collins AJ (2006) Clinical epidemiology of pneumonia in hemodialysis patients: the USRDS waves 1, 3, and 4 study. Kidney Int 70(6):1135–1141

    Article  CAS  PubMed  Google Scholar 

  62. Wang IK, Lin CL, Lin PC, Liang CC, Liu YL, Chang CT et al (2013) Effectiveness of influenza vaccination in patients with end-stage renal disease receiving hemodialysis: a population-based study. PLOS ONE 8(3):e58317

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  63. Cates CJ, Rowe BH (2013) Vaccines for preventing influenza in people with asthma. Cochrane Database Syst Rev 2:CD000364. doi:10.1002/14651858.cd000364.pub4

    Google Scholar 

  64. Bueving HJ, Bernsen RM, de Jongste JC, van Suijlekom-Smit LW, Rimmelzwaan GF, Osterhaus AD et al (2004) Influenza vaccination in children with asthma: randomized double-blind placebo-controlled trial. Am J Respir Crit Care Med 169(4):488–493

    Article  PubMed  Google Scholar 

  65. Govaert TM, Thijs CT, Masurel N, Sprenger MJ, Dinant GJ, Knottnerus JA (1994) The efficacy of influenza vaccination in elderly individuals. A randomized double-blind placebo-controlled trial. JAMA 272(21):1661–1665

    Article  CAS  PubMed  Google Scholar 

  66. Kmiecik T, Arnoux S, Kobryn A, Gorski P (2007) Influenza vaccination in adults with asthma: safety of an inactivated trivalent influenza vaccine. J Asthma 44(10):817–822

    Article  CAS  PubMed  Google Scholar 

  67. Nicholson KG, Nguyen-Van-Tam JS, Ahmed AH, Wiselka MJ, Leese J, Ayres J et al (1998) Randomised placebo-controlled crossover trial on effect of inactivated influenza vaccine on pulmonary function in asthma. Lancet 351(9099):326–331

    Article  CAS  PubMed  Google Scholar 

  68. Udell JA, Zawi R, Bhatt DL, Keshtkar-Jahromi M, Gaughran F, Phrommintikul A et al (2013) Association between influenza vaccination and cardiovascular outcomes in high-risk patients: a meta-analysis. JAMA 310(16):1711–1720

    Article  CAS  PubMed  Google Scholar 

  69. De Villiers PJ, Steele AD, Hiemstra LA, Rappaport R, Dunning AJ, Gruber WC et al (2009) Efficacy and safety of a live attenuated influenza vaccine in adults 60 years of age and older. Vaccine 28(1):228–234

    Article  PubMed  CAS  Google Scholar 

  70. Ahmed F, Lindley MC, Allred N, Weinbaum CM, Grohskopf L (2014) Effect of influenza vaccination of healthcare personnel on morbidity and mortality among patients: systematic review and grading of evidence. Clin Infect Dis 58(1):50–57

    Article  PubMed  Google Scholar 

  71. Jefferson T, Di Pietrantonj C, Rivetti A, Bawazeer GA, Al-Ansary LA, Ferroni E (2014) Vaccines for preventing influenza in healthy adults. Cochrane Database Syst Rev 3:CD001269

    Google Scholar 

  72. Galvao TF, Silva MT, Zimmermann IR, Lopes LA, Bernardo EF, Pereira MG (2013) Influenza vaccination in pregnant women: a systematic review. Isrn Prev Med 2013:879493

    Article  PubMed  PubMed Central  Google Scholar 

  73. Fell DB, Platt RW, Lanes A, Wilson K, Kaufman JS, Basso O et al (2015) Fetal death and preterm birth associated with maternal influenza vaccination: systematic review. BJOG 122(1):17–26

    Article  CAS  PubMed  Google Scholar 

  74. McMillan M, Kralik D, Porritt K, Marshall H (2014) Influenza vaccination during pregnancy: a systematic review of effectiveness and adverse events. JBI Database Syst Rev Implement Rep 12(6):2014

    Google Scholar 

  75. Madhi SA, Cutland CL, Kuwanda L, Weinberg A, Hugo A, Jones S et al (2014) Influenza vaccination of pregnant women and protection of their infants. N Engl J Med 371(10):918–931

    Article  PubMed  CAS  Google Scholar 

  76. Black SB, Shinefield HR, France EK, Fireman BH, Platt ST, Shay D et al (2004) Effectiveness of influenza vaccine during pregnancy in preventing hospitalizations and outpatient visits for respiratory illness in pregnant women and their infants. Am J Perinatol 21(6):333–339

    Article  PubMed  Google Scholar 

  77. Munoz FM, Greisinger AJ, Wehmanen OA, Mouzoon ME, Hoyle JC, Smith FA et al (2005) Safety of influenza vaccination during pregnancy. Am J Obstet Gynecol 192(4):1098–1106

    Article  PubMed  Google Scholar 

  78. Nordin JD, Kharbanda EO, Benitez GV, Nichol K, Lipkind H, Naleway A et al (2013) Maternal safety of trivalent inactivated influenza vaccine in pregnant women. Obstet Gynecol 121(3):519–525

    Article  PubMed  Google Scholar 

  79. Thompson MG, Li DK, Shifflett P, Sokolow LZ, Ferber JR, Kurosky S et al (2014) Effectiveness of seasonal trivalent influenza vaccine for preventing influenza virus illness among pregnant women: a population-based case-control study during the 2010–2011 and 2011–2012 influenza seasons. Clin Infect Dis 58(4):449–457

    Article  PubMed  Google Scholar 

  80. Zaman K, Roy E, Arifeen SE, Rahman M, Raqib R, Wilson E et al (2008) Effectiveness of maternal influenza immunization in mothers and infants. N Engl J Med 359(15):1555–1564

    Article  CAS  PubMed  Google Scholar 

  81. Benowitz I, Esposito DB, Gracey KD, Shapiro ED, Vazquez M (2010) Influenza vaccine given to pregnant women reduces hospitalization due to influenza in their infants. Clin Infect Dis 51(12):1355–1361

    Article  PubMed  PubMed Central  Google Scholar 

  82. Dodds L, Macdonald N, Scott J, Spencer A, Allen VM, McNeil S (2012) The association between influenza vaccine in pregnancy and adverse neonatal outcomes. J Obstet Gynaecol Can 34(8):714–720

    Article  PubMed  Google Scholar 

  83. Eick AA, Uyeki TM, Klimov A, Hall H, Reid R, Santosham M et al (2011) Maternal influenza vaccination and effect on influenza virus infection in young infants. Arch Pediatr Adolesc Med 165(2):104–111

    Article  PubMed  Google Scholar 

  84. France EK, Smith-Ray R, McClure D, Hambidge S, Xu S, Yamasaki K et al (2006) Impact of maternal influenza vaccination during pregnancy on the incidence of acute respiratory illness visits among infants. Arch Pediatr Adolesc Med 160(12):1277–1283

    Article  PubMed  Google Scholar 

  85. Irving SA, Kieke BA, Donahue JG, Mascola MA, Baggs J, DeStefano F et al (2013) Trivalent inactivated influenza vaccine and spontaneous abortion. Obstet Gynecol 121(1):159–165

    Article  PubMed  Google Scholar 

  86. Legge A, Dodds L, MacDonald NE, Scott J, McNeil S (2014) Rates and determinants of seasonal influenza vaccination in pregnancy and association with neonatal outcomes. CMAJ 186(4):E157–E164

    Article  PubMed  PubMed Central  Google Scholar 

  87. Louik C, Ahrens K, Kerr S, Pyo J, Chambers C, Jones KL et al (2013) Risks and safety of pandemic H1N1 influenza vaccine in pregnancy: exposure prevalence, preterm delivery, and specific birth defects. Vaccine 31(44):5033–5040

    Article  CAS  PubMed  Google Scholar 

  88. Omer SB, Goodman D, Steinhoff MC, Rochat R, Klugman KP, Stoll BJ et al (2011) Maternal influenza immunization and reduced likelihood of prematurity and small for gestational age births: a retrospective cohort study. PLOS Med 8(5):e1000441

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  89. Poehling KA, Szilagyi PG, Staat MA, Snively BM, Payne DC, Bridges CB et al (2011) Impact of maternal immunization on influenza hospitalizations in infants. Am J Obstet Gynecol 204(6 Suppl 1):141–148

    Article  Google Scholar 

  90. Sheffield JS, Greer LG, Rogers VL, Roberts SW, Lytle H, McIntire DD et al (2012) Effect of influenza vaccination in the first trimester of pregnancy. Obstet Gynecol 120(3):532–537

    Article  PubMed  Google Scholar 

  91. Jefferson T, Di Pietrantonj C, Al-Ansary LA, Ferroni E, Thorning S, Thomas RE (2010) Vaccines for preventing influenza in the elderly. Cochrane Database Syst Rev 2:CD004876

    Google Scholar 

  92. Darvishian M, Bijlsma MJ, Hak E, van den Heuvel ER (2014) Effectiveness of seasonal influenza vaccine in community-dwelling elderly people: a meta-analysis of test-negative design case-control studies. Lancet Infect Dis 14(12):1228–1239

    Article  PubMed  Google Scholar 

  93. Remschmidt C, Wichmann O, Harder T (2015) Frequency and impact of confounding by indication and healthy vaccinee bias in observational studies assessing influenza vaccine effectiveness: a systematic review. BMC Infect Dis 15:429

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  94. Rudenko LG, Arden NH, Grigorieva E, Naychin A, Rekstin A, Klimov AI et al (2000) Immunogenicity and efficacy of Russian live attenuated and US inactivated influenza vaccines used alone and in combination in nursing home residents. Vaccine 19(2–3):308–318

    Article  CAS  PubMed  Google Scholar 

  95. European Center for Disease Prevention and Control. Indicators of influenza activity. http://ecdc.europa.eu/en/healthtopics/influenza/surveillance/Pages/indicators_influenza.aspx. Accessed on 27.01.2016.

  96. Castilla J, Martinez-Baz I, Martinez-Artola V, Reina G, Pozo F, Garcia Cenoz M et al (2013) Decline in influenza vaccine effectiveness with time after vaccination, Navarre, Spain, season 2011/12. Euro Surveill 18:5

    Google Scholar 

  97. Choi WS, Noh JY, Seo YB, Baek JH, Lee J, Song JY et al (2013) Case-control study of the effectiveness of the 2010-2011 seasonal influenza vaccine for prevention of laboratory-confirmed influenza virus infection in the Korean adult population. Clin Vaccine Immunol 20(6):877–881

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  98. Fleming DM, Andrews NJ, Ellis JS, Bermingham A, Sebastianpillai P, Elliot AJ et al (2010) Estimating influenza vaccine effectiveness using routinely collected laboratory data. J Epidemiol Community Health 64(12):1062–1067

    Article  CAS  PubMed  Google Scholar 

  99. Jimenez-Jorge S, de Mateo S, Delgado-Sanz C, Pozo F, Casas I, Garcia-Cenoz M et al (2013) Effectiveness of influenza vaccine against laboratory-confirmed influenza, in the late 2011–2012 season in Spain, among population targeted for vaccination. BMC Infect Dis 13:441

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  100. Kelly H, Carville K, Grant K, Jacoby P, Tran T, Barr I (2009) Estimation of influenza vaccine effectiveness from routine surveillance data. PLOS ONE 4(3):e5079

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  101. Ohmit SE, Thompson MG, Petrie JG, Thaker SN, Jackson ML, Belongia EA et al (2014) Influenza vaccine effectiveness in the 2011–2012 season: protection against each circulating virus and the effect of prior vaccination on estimates. Clin Infect Dis 58(3):319–327

    Article  PubMed  Google Scholar 

  102. Pebody RG, Andrews N, Fleming DM, McMenamin J, Cottrell S, Smyth B et al (2013) Age-specific vaccine effectiveness of seasonal 2010/2011 and pandemic influenza A(H1N1) 2009 vaccines in preventing influenza in the United Kingdom. Epidemiol Infect 141(3):620–630

    Article  CAS  PubMed  Google Scholar 

  103. Savulescu C, Valenciano M, de Mateo S, Larrauri A (2010) Estimating the influenza vaccine effectiveness in elderly on a yearly basis using the Spanish influenza surveillance network-pilot case-control studies using different control groups, 2008–2009 season, Spain. Vaccine 28(16):2903–2907

    Article  PubMed  Google Scholar 

  104. Treanor JJ, Talbot HK, Ohmit SE, Coleman LA, Thompson MG, Cheng PY et al (2012) Effectiveness of seasonal influenza vaccines in the United States during a season with circulation of all three vaccine strains. Clin Infect Dis 55(7):951–959

    Article  PubMed  PubMed Central  Google Scholar 

  105. Cheng AC, Holmes M, Irving LB, Brown SG, Waterer GW, Korman TM et al (2013) Influenza vaccine effectiveness against hospitalisation with confirmed influenza in the 2010–11 seasons: a test-negative observational study. PLOS ONE 8(7):e68760

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  106. Kwong JC, Campitelli MA, Gubbay JB, Peci A, Winter AL, Olsha R et al (2013) accine effectiveness against laboratory-confirmed influenza hospitalizations among elderly adults during the 2010–2011 season. Clin Infect Dis 57(6):820–827

    Article  PubMed  PubMed Central  Google Scholar 

  107. Puig-Barbera J, Natividad-Sancho A, Launay O, Burtseva E, Ciblak MA, Tormos A et al (2014) 2012–2013 Seasonal influenza vaccine effectiveness against influenza hospitalizations: results from the global influenza hospital surveillance network. PLOS ONE 9(6):e100497

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Danksagung

Die Autoren danken Dr. Silke Buda und Dr. Udo Buchholz vom Robert Koch-Institut, Fachgebiet für respiratorisch übertragbare Erkrankungen, für ihre inhaltlich wertvollen Beiträge und für die kritische Durchsicht des Manuskripts.

Author information

Authors and Affiliations

  1. Fachgebiet Impfprävention, Robert Koch-Institut, Seestraße 10, 13353, Berlin, Deutschland

    Cornelius Remschmidt, Thomas Harder & Ole Wichmann

  2. Klinische Epidemiologie, Leibniz-Institut für Präventionsforschung und Epidemiologie – BIPS GmbH, Bremen, Deutschland

    Edeltraut Garbe

  3. Abteilung Allgemeinmedizin und Versorgungsforschung, Universitätsklinikum Heidelberg, Heidelberg, Deutschland

    Thomas Ledig

  4. Medizinisches Versorgungszentrum am Hermannplatz, Berlin, Deutschland

    Martin Terhardt

  5. Betriebsärztlicher Dienst, Universitätsklinikum Frankfurt, Frankfurt am Main, Deutschland

    Sabine Wicker

  6. Zentrum für Kinder- und Jugendmedizin, Universitätsmedizin Mainz, Mainz, Deutschland

    Fred Zepp

  7. Institut für Virologie, Universitätsklinikum Ulm, Ulm, Deutschland

    Thomas Mertens

Authors
  1. Cornelius Remschmidt
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Thomas Harder
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ole Wichmann
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Edeltraut Garbe
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Thomas Ledig
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Martin Terhardt
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Sabine Wicker
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. Fred Zepp
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. Thomas Mertens
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Cornelius Remschmidt.

Ethics declarations

Interessenkonflikt

C. Remschmidt, T. Harder, O. Wichmann, T. Ledig, S. Wicker und T. Mertens geben an, dass kein Interessenkonflikt besteht. E. Garbe erhielt finanzielle Unterstützung bei der Durchführung von klinischen Studien von GSK und Sanofi Pasteur MSD und erhielt ein Honorar von GSK als Mitglied eines Scientific Advisory Boards. M. Terhardt erhielt Honorare für produktunabhängige Fortbildungsvorträge, die von impfstoffherstellenden Firmen (AstraZeneca, Sanofi Pasteur MSD, GSK) refinanziert wurden. F. Zepp erhielt die Erstattung von Reise- und Übernachtungskosten für produktunabhängige Fortbildungsvorträge die von impfstoffherstellenden Firmen (Sanofi Pasteur MSD, Takeda) refinanziert wurden. Für die Durchführung von klinischen Studien erhielt die Universität Mainz Kostenerstattung.

Electronic Supplementary Material

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Remschmidt, C., Harder, T., Wichmann, O. et al. Hintergrundpapier der STIKO: Evaluation der bestehenden Influenzaimpfempfehlung für Indikationsgruppen und für Senioren (Standardimpfung ab 60 Jahren). Bundesgesundheitsbl 59, 1606–1622 (2016). https://doi.org/10.1007/s00103-016-2467-8

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s00103-016-2467-8

Search

Navigation